Restitution of streptozotocin induced diabetes mellitus in nude mice with pancreatic grafts from the rat

K Buschard; J Rygaard

doi:10.1111/j.1699-0463.1976.tb00023.x

Restitution of streptozotocin induced diabetes mellitus in nude mice with pancreatic grafts from the rat

K Buschard, J Rygaard

9 Citationer (Scopus)

Abstract

Transplants of 1-3 rat pancreases have proven to restitute streptozotocin induced diabetes in athymic nude mice. One out of 9 diabetic nude mice showed restitution following subcutaneous implantation of 1 rat pancreas. Three out of 6 nude mice were restituted by 2-3 grafts. Implants of rat submandibular gland did not restitute nude mice similarly treated with streptozotocin. The model seems of interest in studies of inter-species transplantation of pancreas.

Originalsprog	Engelsk
Tidsskrift	Acta pathologica et microbiologica Scandinavica. Section C, Immunology
Vol/bind	84
Udgave nummer	3
Sider (fra-til)	221-6
Antal sider	6
ISSN	0304-1328
DOI	https://doi.org/10.1111/j.1699-0463.1976.tb00023.x
Status	Udgivet - jun. 1976
Udgivet eksternt	Ja

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10.1111/j.1699-0463.1976.tb00023.x

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title = "Restitution of streptozotocin induced diabetes mellitus in nude mice with pancreatic grafts from the rat",

abstract = "Transplants of 1-3 rat pancreases have proven to restitute streptozotocin induced diabetes in athymic nude mice. One out of 9 diabetic nude mice showed restitution following subcutaneous implantation of 1 rat pancreas. Three out of 6 nude mice were restituted by 2-3 grafts. Implants of rat submandibular gland did not restitute nude mice similarly treated with streptozotocin. The model seems of interest in studies of inter-species transplantation of pancreas.",

keywords = "Animals, Diabetes Mellitus/chemically induced, Female, Male, Mice, Mice, Nude, Pancreas Transplantation, Rats, Streptozocin, Submandibular Gland/transplantation, Transplantation, Heterologous",

author = "K Buschard and J Rygaard",

year = "1976",

month = jun,

doi = "10.1111/j.1699-0463.1976.tb00023.x",

language = "English",

volume = "84",

pages = "221--6",

journal = "Acta pathologica et microbiologica Scandinavica. Section C, Immunology",

issn = "0304-1328",

publisher = "Wiley-Blackwell Publishing Ltd",

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TY - JOUR

T1 - Restitution of streptozotocin induced diabetes mellitus in nude mice with pancreatic grafts from the rat

AU - Buschard, K

AU - Rygaard, J

PY - 1976/6

Y1 - 1976/6

N2 - Transplants of 1-3 rat pancreases have proven to restitute streptozotocin induced diabetes in athymic nude mice. One out of 9 diabetic nude mice showed restitution following subcutaneous implantation of 1 rat pancreas. Three out of 6 nude mice were restituted by 2-3 grafts. Implants of rat submandibular gland did not restitute nude mice similarly treated with streptozotocin. The model seems of interest in studies of inter-species transplantation of pancreas.

AB - Transplants of 1-3 rat pancreases have proven to restitute streptozotocin induced diabetes in athymic nude mice. One out of 9 diabetic nude mice showed restitution following subcutaneous implantation of 1 rat pancreas. Three out of 6 nude mice were restituted by 2-3 grafts. Implants of rat submandibular gland did not restitute nude mice similarly treated with streptozotocin. The model seems of interest in studies of inter-species transplantation of pancreas.

KW - Animals

KW - Diabetes Mellitus/chemically induced

KW - Female

KW - Male

KW - Mice

KW - Mice, Nude

KW - Pancreas Transplantation

KW - Rats

KW - Streptozocin

KW - Submandibular Gland/transplantation

KW - Transplantation, Heterologous

UR - https://www.scopus.com/pages/publications/0017116245

U2 - 10.1111/j.1699-0463.1976.tb00023.x

DO - 10.1111/j.1699-0463.1976.tb00023.x

M3 - Journal article

C2 - 136861

SN - 0304-1328

VL - 84

SP - 221

EP - 226

JO - Acta pathologica et microbiologica Scandinavica. Section C, Immunology

JF - Acta pathologica et microbiologica Scandinavica. Section C, Immunology

IS - 3

ER -

Restitution of streptozotocin induced diabetes mellitus in nude mice with pancreatic grafts from the rat

Abstract

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