TY - JOUR
T1 - Respiratory syncytial virus and influenza hospitalizations in Danish children 2010-2016
AU - Jensen, Andreas
AU - A F Simões, Eric
AU - Bohn Christiansen, Claus
AU - Graff Stensballe, Lone
N1 - Copyright © 2021 Elsevier Ltd. All rights reserved.
PY - 2021/7/5
Y1 - 2021/7/5
N2 - OBJECTIVE: To pave the way for universal or risk factor-based vaccination strategies, the present study aimed to describe the epidemiology and compare risk factors for hospitalization associated with respiratory syncytial virus (RSV) and influenza virus infections in Danish children.METHODS: National register-based cohort study among 403,422 Danish children born 2010-2016.RESULTS: Prior asthma hospitalization, number of children in the household, chronic disease and maternal history of asthma hospitalization were the most important risk factors for both RSV and influenza hospitalization. The incidence of influenza increased at school start.CONCLUSIONS: Our findings enable targeted vaccination programs for high-risk children with asthma-like disease, chronic disease, siblings in the household, or maternal history of asthma hospitalization.
AB - OBJECTIVE: To pave the way for universal or risk factor-based vaccination strategies, the present study aimed to describe the epidemiology and compare risk factors for hospitalization associated with respiratory syncytial virus (RSV) and influenza virus infections in Danish children.METHODS: National register-based cohort study among 403,422 Danish children born 2010-2016.RESULTS: Prior asthma hospitalization, number of children in the household, chronic disease and maternal history of asthma hospitalization were the most important risk factors for both RSV and influenza hospitalization. The incidence of influenza increased at school start.CONCLUSIONS: Our findings enable targeted vaccination programs for high-risk children with asthma-like disease, chronic disease, siblings in the household, or maternal history of asthma hospitalization.
KW - Child
KW - Cohort Studies
KW - Denmark/epidemiology
KW - Hospitalization
KW - Humans
KW - Infant
KW - Influenza, Human/epidemiology
KW - Respiratory Syncytial Virus Infections/epidemiology
KW - Respiratory Syncytial Virus, Human
KW - Risk Factors
UR - http://www.scopus.com/inward/record.url?scp=85107658903&partnerID=8YFLogxK
U2 - 10.1016/j.vaccine.2021.05.097
DO - 10.1016/j.vaccine.2021.05.097
M3 - Journal article
C2 - 34116876
SN - 0264-410X
VL - 39
SP - 4126
EP - 4134
JO - Vaccine
JF - Vaccine
IS - 30
ER -