Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Reproductive endocrinology of vitamin D

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Experimental models of testicular development and function using human tissue and cells

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  2. Circulating follistatin in relation to energy metabolism

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. High maternal age at first and subsequent child births in Denmark in the mid-1800s-Letter to the editor

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Characterisation and localisation of the endocannabinoid system components in the adult human testis

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Possible link between FSH and RANKL release from adipocytes in men with impaired gonadal function including Klinefelter syndrome

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Characterization of Human Adrenal Steroidogenesis during Fetal Development

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Populations, decreasing fertility, and reproductive health

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

Vitamin D is a versatile hormone with several functions beyond its well-established role in maintenance of skeletal health and calcium homeostasis. The effects of vitamin D are mediated by the vitamin D receptor, which is expressed together with the vitamin D metabolizing enzymes in the reproductive tissues. The reproductive organs are therefore responsive to and able to metabolize vitamin D locally. The exact role remains to be clarified but several studies have suggested a link between vitamin D and production/release of reproductive hormones into circulation, which will be the main focus of this review. Current evidence is primarily based on small human association studies and rodent models. This highlights the need for randomized clinical trials, but also functional animal and human in vitro studies, and larger, prospective cohort studies are warranted. Given the high number of men and women suffering from reproductive problems and abnormal endocrinology research addressing the role of vitamin D in reproductive endocrinology is of clinical importance.

OriginalsprogEngelsk
TidsskriftMolecular and Cellular Endocrinology
Vol/bind453
Sider (fra-til)103-112
ISSN0303-7207
DOI
StatusUdgivet - 15 sep. 2017

ID: 50151076