Replication and meta-analysis of common variants identifies a genome-wide significant locus in migraine

A L Esserlind, Anne Francke Christensen, H Le, M Kirchmann, A W Hauge, N M Toyserkani, Torben Lindskov Hansen, Niels Grarup, T Werge, S Steinberg, F Bettella, H Stefansson, Jes Olesen

65 Citationer (Scopus)

Abstract

BACKGROUND AND PURPOSE: Genetic factors contribute to the aetiology of the prevalent form of migraine without aura (MO) and migraine with typical aura (MTA). Due to the complex inheritance of MO and MTA, the genetic background is still not fully established. In a population-based genome-wide association study by Chasman et al. (Nat Genet 2011: 43: 695-698), three common variants were found to confer risk of migraine at a genome-wide significant level (P 
OriginalsprogEngelsk
TidsskriftEuropean Journal of Neurology
Sider (fra-til)765-772
Antal sider8
ISSN1351-5101
DOI
StatusUdgivet - maj 2013

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