Repeated exposure to hair dye induces regulatory T cells in mice

I M C Rubin; S Dabelsteen; M M Nielsen; I R White; J D Johansen; C Geisler; C M Bonefeld

doi:10.1111/j.1365-2133.2010.09988.x

Repeated exposure to hair dye induces regulatory T cells in mice

I M C Rubin, S Dabelsteen, M M Nielsen, I R White, J D Johansen, C Geisler, C M Bonefeld

Allergi, Hud- og Kønssygdomme

24 Citationer (Scopus)

Abstract

We have recently shown that commercial p-phenylenediamine (PPD)-containing hair dyes are potent immune activators that lead to severe contact hypersensitivity in an animal model. However, only a minority of people exposed to permanent hair dyes develops symptomatic contact hypersensitivity. This suggests that the majority of people exposed to hair dyes does not become sensitized or develop immunological tolerance.

Originalsprog	Engelsk
Tidsskrift	British Journal of Dermatology
Vol/bind	163
Udgave nummer	5
Sider (fra-til)	992-8
Antal sider	7
ISSN	0007-0963
DOI	https://doi.org/10.1111/j.1365-2133.2010.09988.x
Status	Udgivet - 1 nov. 2010

Adgang til dokumentet

10.1111/j.1365-2133.2010.09988.x

Citationsformater

@article{c1c6c74b83564e149d2a5cdc9d4298bc,

title = "Repeated exposure to hair dye induces regulatory T cells in mice",

abstract = "We have recently shown that commercial p-phenylenediamine (PPD)-containing hair dyes are potent immune activators that lead to severe contact hypersensitivity in an animal model. However, only a minority of people exposed to permanent hair dyes develops symptomatic contact hypersensitivity. This suggests that the majority of people exposed to hair dyes does not become sensitized or develop immunological tolerance.",

author = "Rubin, {I M C} and S Dabelsteen and Nielsen, {M M} and White, {I R} and Johansen, {J D} and C Geisler and Bonefeld, {C M}",

note = "{\textcopyright} 2010 The Authors. BJD {\textcopyright} 2010 British Association of Dermatologists.",

year = "2010",

month = nov,

day = "1",

doi = "10.1111/j.1365-2133.2010.09988.x",

language = "English",

volume = "163",

pages = "992--8",

journal = "British Journal of Dermatology",

issn = "0007-0963",

publisher = "Wiley-Blackwell Publishing Ltd",

number = "5",

}

TY - JOUR

T1 - Repeated exposure to hair dye induces regulatory T cells in mice

AU - Rubin, I M C

AU - Dabelsteen, S

AU - Nielsen, M M

AU - White, I R

AU - Johansen, J D

AU - Geisler, C

AU - Bonefeld, C M

PY - 2010/11/1

Y1 - 2010/11/1

N2 - We have recently shown that commercial p-phenylenediamine (PPD)-containing hair dyes are potent immune activators that lead to severe contact hypersensitivity in an animal model. However, only a minority of people exposed to permanent hair dyes develops symptomatic contact hypersensitivity. This suggests that the majority of people exposed to hair dyes does not become sensitized or develop immunological tolerance.

AB - We have recently shown that commercial p-phenylenediamine (PPD)-containing hair dyes are potent immune activators that lead to severe contact hypersensitivity in an animal model. However, only a minority of people exposed to permanent hair dyes develops symptomatic contact hypersensitivity. This suggests that the majority of people exposed to hair dyes does not become sensitized or develop immunological tolerance.

U2 - 10.1111/j.1365-2133.2010.09988.x

DO - 10.1111/j.1365-2133.2010.09988.x

M3 - Journal article

C2 - 20716223

SN - 0007-0963

VL - 163

SP - 992

EP - 998

JO - British Journal of Dermatology

JF - British Journal of Dermatology

IS - 5

ER -

Repeated exposure to hair dye induces regulatory T cells in mice

Abstract

Adgang til dokumentet

Fingeraftryk

Citationsformater