Renal and cardiac function during alpha1-beta-blockade in congestive heart failure

M Heitmann; U Davidsen; K H Stokholm; K Rasmussen; H Burchardt; E B Petersen

doi:10.1080/003655102753611717

Renal and cardiac function during alpha1-beta-blockade in congestive heart failure

M Heitmann, U Davidsen, K H Stokholm, K Rasmussen, H Burchardt, E B Petersen

Hjerteafd. Y

15 Citationer (Scopus)

Abstract

The kidney and the neurohormonal systems are essential in the pathogenesis of congestive heart failure (CHF) and the physiologic response. Routine treatment of moderate to severe CHF consists of diuretics, angiotensin-converting enzyme (ACE) inhibition and beta-blockade. The need for control of renal function during initiation of ACE-inhibition in patients with CHF is well known. The aim of this study was to investigate whether supplementation by a combined alpha1-beta-blockade to diuretics and ACE-inhibition might improve cardiac function without reducing renal function.

Originalsprog	Engelsk
Tidsskrift	Scandinavian Journal of Clinical & Laboratory Investigation
Vol/bind	62
Udgave nummer	2
Sider (fra-til)	97-104
Antal sider	8
ISSN	0036-5513
DOI	https://doi.org/10.1080/003655102753611717
Status	Udgivet - 2002

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10.1080/003655102753611717

Citationsformater

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title = "Renal and cardiac function during alpha1-beta-blockade in congestive heart failure",

abstract = "The kidney and the neurohormonal systems are essential in the pathogenesis of congestive heart failure (CHF) and the physiologic response. Routine treatment of moderate to severe CHF consists of diuretics, angiotensin-converting enzyme (ACE) inhibition and beta-blockade. The need for control of renal function during initiation of ACE-inhibition in patients with CHF is well known. The aim of this study was to investigate whether supplementation by a combined alpha1-beta-blockade to diuretics and ACE-inhibition might improve cardiac function without reducing renal function.",

keywords = "Adrenergic beta-Antagonists, Aged, Aldosterone, Angiotensin II, Angiotensin-Converting Enzyme Inhibitors, Blood Pressure, Carbazoles, Cardiac Output, Diuretics, Drug Therapy, Combination, Glomerular Filtration Rate, Heart, Heart Failure, Heart Rate, Humans, Kidney, Middle Aged, Propanolamines, Renal Circulation",

author = "M Heitmann and U Davidsen and Stokholm, {K H} and K Rasmussen and H Burchardt and Petersen, {E B}",

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T1 - Renal and cardiac function during alpha1-beta-blockade in congestive heart failure

AU - Heitmann, M

AU - Davidsen, U

AU - Stokholm, K H

AU - Rasmussen, K

AU - Burchardt, H

AU - Petersen, E B

PY - 2002

Y1 - 2002

N2 - The kidney and the neurohormonal systems are essential in the pathogenesis of congestive heart failure (CHF) and the physiologic response. Routine treatment of moderate to severe CHF consists of diuretics, angiotensin-converting enzyme (ACE) inhibition and beta-blockade. The need for control of renal function during initiation of ACE-inhibition in patients with CHF is well known. The aim of this study was to investigate whether supplementation by a combined alpha1-beta-blockade to diuretics and ACE-inhibition might improve cardiac function without reducing renal function.

AB - The kidney and the neurohormonal systems are essential in the pathogenesis of congestive heart failure (CHF) and the physiologic response. Routine treatment of moderate to severe CHF consists of diuretics, angiotensin-converting enzyme (ACE) inhibition and beta-blockade. The need for control of renal function during initiation of ACE-inhibition in patients with CHF is well known. The aim of this study was to investigate whether supplementation by a combined alpha1-beta-blockade to diuretics and ACE-inhibition might improve cardiac function without reducing renal function.

KW - Adrenergic beta-Antagonists

KW - Aged

KW - Aldosterone

KW - Angiotensin II

KW - Angiotensin-Converting Enzyme Inhibitors

KW - Blood Pressure

KW - Carbazoles

KW - Cardiac Output

KW - Diuretics

KW - Drug Therapy, Combination

KW - Glomerular Filtration Rate

KW - Heart

KW - Heart Failure

KW - Heart Rate

KW - Humans

KW - Kidney

KW - Middle Aged

KW - Propanolamines

KW - Renal Circulation

U2 - 10.1080/003655102753611717

DO - 10.1080/003655102753611717

M3 - Journal article

C2 - 12004934

SN - 0036-5513

VL - 62

SP - 97

EP - 104

JO - Scandinavian Journal of Clinical & Laboratory Investigation

JF - Scandinavian Journal of Clinical & Laboratory Investigation

IS - 2

ER -

Renal and cardiac function during alpha1-beta-blockade in congestive heart failure

Abstract

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