Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Reliability of the transcranial Doppler ultrasound-derived mean flow index for assessing dynamic cerebral autoregulation in healthy volunteers

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. New equations to calculate 3D joint centres in the lower extremities

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Minimal model quantification of pulmonary gas exchange in intensive care patients

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. An active learning approach to the physics of medical imaging

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. On-line analysis of middle latency auditory evoked potentials (MLAEP) for monitoring depth of anaesthesia in laboratory rats

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Training non-intensivist doctors to work with COVID-19 patients in intensive care units

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Prediction of survival in amyotrophic lateral sclerosis: a nationwide, Danish cohort study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Classification of orthostatic intolerance through data analytics

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

The transcranial Doppler ultrasound-derived mean flow index (Mxa) is widely used for assessing dynamic cerebral autoregulation (dCA) in different clinical populations. This study aimed at estimating the relative and absolute reliability of Mxa in healthy participants in the supine position and during head-up tilt (HUT). Fourteen healthy participants were examined on two separate occasions during which, mean middle cerebral artery blood flow velocity (MCAv), non-invasive blood pressure, and heart rate were continuously recorded in the supine position and during HUT. Mxa was calculated as the correlation coefficient between mean arterial blood pressure and MCAv using either 3-, 5-, or 10-second averages collected over a 300 second period. Intraclass correlation coefficient (ICC1.1) was calculated to assess relative reliability, while the standard error of measurement (SEM), and limits of agreement (LOA) were used to assess absolute reliability. Mxa-based 3-second averages yielded a similar relative and absolute reliability in both positions. When Mxa was calculated from 5-second averages, the most reliable values were obtained during HUT. The poorest reliability was achieved using 10-second averages, regardless of posture. The Mxa shows fair reliability with acceptable LOA in healthy volunteers when based on 3-second averages, both in the supine position and during HUT.

OriginalsprogEngelsk
TidsskriftMedical Engineering & Physics
Vol/bind89
Antal sider6
ISSN1350-4533
DOI
StatusUdgivet - 2021

Bibliografisk note

Copyright © 2021. Published by Elsevier Ltd.

ID: 62386465