Relationship between cerebrospinal fluid biomarkers for inflammation, demyelination and neurodegeneration in acute optic neuritis

Signe Modvig; Matilda Degn; Henrik Horwitz; Stig Præstekær  Cramer; Henrik B W Larsson; Benedikte Wanscher; Finn Sellebjerg; Jette L Frederiksen

doi:10.1371/journal.pone.0077163

Relationship between cerebrospinal fluid biomarkers for inflammation, demyelination and neurodegeneration in acute optic neuritis

Signe Modvig, Matilda Degn, Henrik Horwitz, Stig Præstekær Cramer , Henrik B W Larsson, Benedikte Wanscher, Finn Sellebjerg, Jette L Frederiksen

56 Citationer (Scopus)

Abstract

Various inflammatory biomarkers show prognostic potential for multiple sclerosis (MS)-risk after clinically isolated syndromes. However, biomarkers are often examined singly and their interrelation and precise aspects of their associated pathological processes remain unclear. Clarification of these relationships could aid the appropriate implementation of prognostic biomarkers in clinical practice.

Originalsprog	Engelsk
Tidsskrift	P L o S One
Vol/bind	8
Udgave nummer	10
Sider (fra-til)	e77163
ISSN	1932-6203
DOI	https://doi.org/10.1371/journal.pone.0077163
Status	Udgivet - 2013

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10.1371/journal.pone.0077163

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title = "Relationship between cerebrospinal fluid biomarkers for inflammation, demyelination and neurodegeneration in acute optic neuritis",

abstract = "Various inflammatory biomarkers show prognostic potential for multiple sclerosis (MS)-risk after clinically isolated syndromes. However, biomarkers are often examined singly and their interrelation and precise aspects of their associated pathological processes remain unclear. Clarification of these relationships could aid the appropriate implementation of prognostic biomarkers in clinical practice.",

author = "Signe Modvig and Matilda Degn and Henrik Horwitz and Cramer, {Stig Pr{\ae}stek{\ae}r} and Larsson, {Henrik B W} and Benedikte Wanscher and Finn Sellebjerg and Frederiksen, {Jette L}",

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TY - JOUR

T1 - Relationship between cerebrospinal fluid biomarkers for inflammation, demyelination and neurodegeneration in acute optic neuritis

AU - Modvig, Signe

AU - Degn, Matilda

AU - Horwitz, Henrik

AU - Cramer , Stig Præstekær

AU - Larsson, Henrik B W

AU - Wanscher, Benedikte

AU - Sellebjerg, Finn

AU - Frederiksen, Jette L

PY - 2013

Y1 - 2013

N2 - Various inflammatory biomarkers show prognostic potential for multiple sclerosis (MS)-risk after clinically isolated syndromes. However, biomarkers are often examined singly and their interrelation and precise aspects of their associated pathological processes remain unclear. Clarification of these relationships could aid the appropriate implementation of prognostic biomarkers in clinical practice.

AB - Various inflammatory biomarkers show prognostic potential for multiple sclerosis (MS)-risk after clinically isolated syndromes. However, biomarkers are often examined singly and their interrelation and precise aspects of their associated pathological processes remain unclear. Clarification of these relationships could aid the appropriate implementation of prognostic biomarkers in clinical practice.

U2 - 10.1371/journal.pone.0077163

DO - 10.1371/journal.pone.0077163

M3 - Journal article

C2 - 24116216

SN - 1932-6203

VL - 8

SP - e77163

JO - P L o S One

JF - P L o S One

IS - 10

ER -

Relationship between cerebrospinal fluid biomarkers for inflammation, demyelination and neurodegeneration in acute optic neuritis

Abstract

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