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Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Regional cerebral blod flow studied by xenon-133. Intra-arterial injection studies and inhalation studies using emission tomography

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Vis graf over relationer
A survey of the Xenon-133 techniques for measurement of regional cerebral blood flow, rCBF, in man is presented. The intra-arterial Xe-133 injection method is very sensitive for detecting even small hyperemic areas, but cannot "see" smaller ischemic areas. The Xe-133 inhalation (or i.v. inj.) technique is insensitive both to hyperemia and ischemia yielding essentially only a mean flow value. A new rapidly moving single photon tomograph following D. Kuhl's principle is presented applicable to Xe-133. Preliminary clinical data show that this technique is able to detect ischemic areas both with Xe-133 intra-arterial injection and with Xe-133 inhalation. The practical and economic advantages of Xe-133 or Xe-127 tomography over positron tomography for rCBF are discussed.
OriginalsprogEngelsk
TidsskriftBulletin der Schweizerischen Akademie der Medizinischen Wissenschaften
Vol/bind36
Udgave nummer1-3
Sider (fra-til)93-100
Antal sider8
ISSN0036-7494
StatusUdgivet - apr. 1980

ID: 39052145