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Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Referral Patterns for Patients with Nonalcoholic Fatty Liver Disease

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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The incidence of nonalcoholic fatty liver disease (NAFLD) is rapidly increasing. This study evaluates the referral pattern of patients with NAFLD. A cohort study evaluating all patients with NAFLD referred to a single Gastroenterology Department from January 2017 to June 2020. Electronic patient referral letters were reviewed, and patients with NAFLD were diagnosed using standardized tests as part of a prospective cohort study. Predictors of nonalcoholic steatohepatitis (NASH) with significant (≥F2) fibrosis were evaluated in logistic regression analyses. In total, 323 (18.6%) of 1735 patients referred to the Gastro Unit during the study period were diagnosed with NAFLD. Patients were referred from general practitioners (62.5%) or other hospital departments (37.5%). Most referral letters included information suggesting a possible diagnosis of NAFLD (patient history, blood tests, or diagnostic imaging) or used the nonspecific general diagnosis suspected disease (Z.038). Out of 110 patients referred for a liver biopsy, 71 (22%) had NASH with significant fibrosis (F2 n = 39, F3 n = 19, F4 n = 13). Thirty-nine of these patients were referred from the primary sector. A logistic regression analysis (adjusted for age and gender) including all 323 patients showed that type 2 diabetes was the only significant independent predictor of NASH with fibrosis.

OriginalsprogEngelsk
Artikelnummer404
TidsskriftJournal of Clinical Medicine
Vol/bind10
Udgave nummer3
Sider (fra-til)1-8
Antal sider8
ISSN2077-0383
DOI
StatusUdgivet - 21 jan. 2021

ID: 61911033