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Reduced prevalence of SARS-CoV-2 infection in ABO blood group O

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Harvard

Barnkob, MB, Pottegård, A, Støvring, H, Haunstrup, TM, Homburg, K, Larsen, R, Hansen, MB, Titlestad, K, Aagaard, B, Møller, BK & Barington, T 2020, 'Reduced prevalence of SARS-CoV-2 infection in ABO blood group O', Blood advances, bind 4, nr. 20, s. 4990-4993. https://doi.org/10.1182/BLOODADVANCES.2020002657

APA

Barnkob, M. B., Pottegård, A., Støvring, H., Haunstrup, T. M., Homburg, K., Larsen, R., Hansen, M. B., Titlestad, K., Aagaard, B., Møller, B. K., & Barington, T. (2020). Reduced prevalence of SARS-CoV-2 infection in ABO blood group O. Blood advances, 4(20), 4990-4993. https://doi.org/10.1182/BLOODADVANCES.2020002657

CBE

Barnkob MB, Pottegård A, Støvring H, Haunstrup TM, Homburg K, Larsen R, Hansen MB, Titlestad K, Aagaard B, Møller BK, Barington T. 2020. Reduced prevalence of SARS-CoV-2 infection in ABO blood group O. Blood advances. 4(20):4990-4993. https://doi.org/10.1182/BLOODADVANCES.2020002657

MLA

Vancouver

Barnkob MB, Pottegård A, Støvring H, Haunstrup TM, Homburg K, Larsen R o.a. Reduced prevalence of SARS-CoV-2 infection in ABO blood group O. Blood advances. 2020 okt 27;4(20):4990-4993. https://doi.org/10.1182/BLOODADVANCES.2020002657

Author

Barnkob, Mike Bogetofte ; Pottegård, Anton ; Støvring, Henrik ; Haunstrup, Thure Mors ; Homburg, Keld ; Larsen, Rune ; Hansen, Morten Bagge ; Titlestad, Kjell ; Aagaard, Bitten ; Møller, Bjarne Kuno ; Barington, Torben. / Reduced prevalence of SARS-CoV-2 infection in ABO blood group O. I: Blood advances. 2020 ; Bind 4, Nr. 20. s. 4990-4993.

Bibtex

@article{de574f7e3f8243be99e1242d1a0f5690,
title = "Reduced prevalence of SARS-CoV-2 infection in ABO blood group O",
abstract = "Identification of risk factors for contracting and developing serious illness following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is of paramount interest. Here, we performed a retrospective cohort analysis of all Danish individuals tested for SARS-CoV-2 between 27 February 2020 and 30 July 2020, with a known ABO and RhD blood group, to determine the influence of common blood groups on virus susceptibility. Distribution of blood groups was compared with data from nontested individuals. Participants (29% of whom were male) included 473 654 individuals tested for SARS-CoV-2 using real-time polymerase chain reaction (7422 positive and 466 232 negative) and 2 204 742 nontested individuals, accounting for ∼38% of the total Danish population. Hospitalization and death from COVID-19, age, cardiovascular comorbidities, and job status were also collected for confirmed infected cases. ABO blood groups varied significantly between patients and the reference group, with only 38.41% (95% confidence interval [CI], 37.30-39.50) of the patients belonging to blood group O compared with 41.70% (95% CI, 41.60-41.80) in the controls, corresponding to a relative risk of 0.87 (95% CI, 0.83-0.91) for acquiring COVID-19. This study identifies ABO blood group as a risk factor for SARS-CoV-2 infection but not for hospitalization or death from COVID-19.",
keywords = "ABO Blood-Group System/blood, Betacoronavirus/isolation & purification, COVID-19, Coronavirus Infections/blood, Denmark/epidemiology, Female, Humans, Male, Pandemics, Pneumonia, Viral/blood, Prevalence, Protective Factors, Retrospective Studies, Risk Factors, SARS-CoV-2",
author = "Barnkob, {Mike Bogetofte} and Anton Potteg{\aa}rd and Henrik St{\o}vring and Haunstrup, {Thure Mors} and Keld Homburg and Rune Larsen and Hansen, {Morten Bagge} and Kjell Titlestad and Bitten Aagaard and M{\o}ller, {Bjarne Kuno} and Torben Barington",
note = "{\textcopyright} 2020 by The American Society of Hematology.",
year = "2020",
month = oct,
day = "27",
doi = "10.1182/BLOODADVANCES.2020002657",
language = "English",
volume = "4",
pages = "4990--4993",
journal = "Blood advances",
issn = "2473-9529",
publisher = "American Society of Hematology",
number = "20",

}

RIS

TY - JOUR

T1 - Reduced prevalence of SARS-CoV-2 infection in ABO blood group O

AU - Barnkob, Mike Bogetofte

AU - Pottegård, Anton

AU - Støvring, Henrik

AU - Haunstrup, Thure Mors

AU - Homburg, Keld

AU - Larsen, Rune

AU - Hansen, Morten Bagge

AU - Titlestad, Kjell

AU - Aagaard, Bitten

AU - Møller, Bjarne Kuno

AU - Barington, Torben

N1 - © 2020 by The American Society of Hematology.

PY - 2020/10/27

Y1 - 2020/10/27

N2 - Identification of risk factors for contracting and developing serious illness following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is of paramount interest. Here, we performed a retrospective cohort analysis of all Danish individuals tested for SARS-CoV-2 between 27 February 2020 and 30 July 2020, with a known ABO and RhD blood group, to determine the influence of common blood groups on virus susceptibility. Distribution of blood groups was compared with data from nontested individuals. Participants (29% of whom were male) included 473 654 individuals tested for SARS-CoV-2 using real-time polymerase chain reaction (7422 positive and 466 232 negative) and 2 204 742 nontested individuals, accounting for ∼38% of the total Danish population. Hospitalization and death from COVID-19, age, cardiovascular comorbidities, and job status were also collected for confirmed infected cases. ABO blood groups varied significantly between patients and the reference group, with only 38.41% (95% confidence interval [CI], 37.30-39.50) of the patients belonging to blood group O compared with 41.70% (95% CI, 41.60-41.80) in the controls, corresponding to a relative risk of 0.87 (95% CI, 0.83-0.91) for acquiring COVID-19. This study identifies ABO blood group as a risk factor for SARS-CoV-2 infection but not for hospitalization or death from COVID-19.

AB - Identification of risk factors for contracting and developing serious illness following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is of paramount interest. Here, we performed a retrospective cohort analysis of all Danish individuals tested for SARS-CoV-2 between 27 February 2020 and 30 July 2020, with a known ABO and RhD blood group, to determine the influence of common blood groups on virus susceptibility. Distribution of blood groups was compared with data from nontested individuals. Participants (29% of whom were male) included 473 654 individuals tested for SARS-CoV-2 using real-time polymerase chain reaction (7422 positive and 466 232 negative) and 2 204 742 nontested individuals, accounting for ∼38% of the total Danish population. Hospitalization and death from COVID-19, age, cardiovascular comorbidities, and job status were also collected for confirmed infected cases. ABO blood groups varied significantly between patients and the reference group, with only 38.41% (95% confidence interval [CI], 37.30-39.50) of the patients belonging to blood group O compared with 41.70% (95% CI, 41.60-41.80) in the controls, corresponding to a relative risk of 0.87 (95% CI, 0.83-0.91) for acquiring COVID-19. This study identifies ABO blood group as a risk factor for SARS-CoV-2 infection but not for hospitalization or death from COVID-19.

KW - ABO Blood-Group System/blood

KW - Betacoronavirus/isolation & purification

KW - COVID-19

KW - Coronavirus Infections/blood

KW - Denmark/epidemiology

KW - Female

KW - Humans

KW - Male

KW - Pandemics

KW - Pneumonia, Viral/blood

KW - Prevalence

KW - Protective Factors

KW - Retrospective Studies

KW - Risk Factors

KW - SARS-CoV-2

UR - http://www.scopus.com/inward/record.url?scp=85096184655&partnerID=8YFLogxK

U2 - 10.1182/BLOODADVANCES.2020002657

DO - 10.1182/BLOODADVANCES.2020002657

M3 - Journal article

C2 - 33057631

VL - 4

SP - 4990

EP - 4993

JO - Blood advances

JF - Blood advances

SN - 2473-9529

IS - 20

ER -

ID: 61697422