Recurrence in affective disorder. I. Case register study

L V Kessing; P K Andersen; P B Mortensen; T G Bolwig

Recurrence in affective disorder. I. Case register study

L V Kessing
, P K Andersen
, P B Mortensen
, T G Bolwig

189 Citationer (Scopus)

Abstract

BACKGROUND: In recent years, studies of the risk of recurrence in affective disorder in relation to the number of prior episodes have given contradictory results.

METHOD: Survival analysis was used to calculate the rate of recurrence after successive episodes in a case register study including all hospital admissions with primary affective disorder in Denmark during 1971-1993. A total of 20,350 first-admission patients were discharged with a diagnosis of affective disorder, depressive or manic/cyclic type.

RESULTS: The rate of recurrence increased with the number of previous episodes in both unipolar and bipolar disorder. Initially, the two types of disorders followed markedly different courses, but later in the course of the illness the rate of recurrence was the same for the two disorders.

CONCLUSIONS: The course of severe unipolar and bipolar disorder seems to be progressive in nature despite the effect of treatment.

Originalsprog	Engelsk
Tidsskrift	The British journal of psychiatry : the journal of mental science
Vol/bind	172
Sider (fra-til)	23-8
Antal sider	6
ISSN	0007-1250
Status	Udgivet - jan. 1998

Citationsformater

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abstract = "BACKGROUND: In recent years, studies of the risk of recurrence in affective disorder in relation to the number of prior episodes have given contradictory results.METHOD: Survival analysis was used to calculate the rate of recurrence after successive episodes in a case register study including all hospital admissions with primary affective disorder in Denmark during 1971-1993. A total of 20,350 first-admission patients were discharged with a diagnosis of affective disorder, depressive or manic/cyclic type.RESULTS: The rate of recurrence increased with the number of previous episodes in both unipolar and bipolar disorder. Initially, the two types of disorders followed markedly different courses, but later in the course of the illness the rate of recurrence was the same for the two disorders.CONCLUSIONS: The course of severe unipolar and bipolar disorder seems to be progressive in nature despite the effect of treatment.",

keywords = "Adult, Bipolar Disorder, Denmark, Depressive Disorder, Female, Hospitalization, Humans, Male, Middle Aged, Mood Disorders, Recurrence, Risk Factors, Sex Factors, Survival Analysis, Survival Rate, Time Factors, Journal Article, Research Support, Non-U.S. Gov't",

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year = "1998",

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journal = "The British journal of psychiatry : the journal of mental science",

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TY - JOUR

T1 - Recurrence in affective disorder. I. Case register study

AU - Kessing, L V

AU - Andersen, P K

AU - Mortensen, P B

AU - Bolwig, T G

PY - 1998/1

Y1 - 1998/1

N2 - BACKGROUND: In recent years, studies of the risk of recurrence in affective disorder in relation to the number of prior episodes have given contradictory results.METHOD: Survival analysis was used to calculate the rate of recurrence after successive episodes in a case register study including all hospital admissions with primary affective disorder in Denmark during 1971-1993. A total of 20,350 first-admission patients were discharged with a diagnosis of affective disorder, depressive or manic/cyclic type.RESULTS: The rate of recurrence increased with the number of previous episodes in both unipolar and bipolar disorder. Initially, the two types of disorders followed markedly different courses, but later in the course of the illness the rate of recurrence was the same for the two disorders.CONCLUSIONS: The course of severe unipolar and bipolar disorder seems to be progressive in nature despite the effect of treatment.

AB - BACKGROUND: In recent years, studies of the risk of recurrence in affective disorder in relation to the number of prior episodes have given contradictory results.METHOD: Survival analysis was used to calculate the rate of recurrence after successive episodes in a case register study including all hospital admissions with primary affective disorder in Denmark during 1971-1993. A total of 20,350 first-admission patients were discharged with a diagnosis of affective disorder, depressive or manic/cyclic type.RESULTS: The rate of recurrence increased with the number of previous episodes in both unipolar and bipolar disorder. Initially, the two types of disorders followed markedly different courses, but later in the course of the illness the rate of recurrence was the same for the two disorders.CONCLUSIONS: The course of severe unipolar and bipolar disorder seems to be progressive in nature despite the effect of treatment.

KW - Adult

KW - Bipolar Disorder

KW - Denmark

KW - Depressive Disorder

KW - Female

KW - Hospitalization

KW - Humans

KW - Male

KW - Middle Aged

KW - Mood Disorders

KW - Recurrence

KW - Risk Factors

KW - Sex Factors

KW - Survival Analysis

KW - Survival Rate

KW - Time Factors

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

M3 - Journal article

C2 - 9534827

SN - 0007-1250

VL - 172

SP - 23

EP - 28

JO - The British journal of psychiatry : the journal of mental science

JF - The British journal of psychiatry : the journal of mental science

ER -

Recurrence in affective disorder. I. Case register study

Abstract

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Citationsformater