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Region Hovedstaden - en del af Københavns Universitetshospital

Recent advances in understanding and managing contact dermatitis

Publikation: Bidrag til tidsskriftReviewForskningpeer review

  1. Increased all-cause mortality in concomitant atopic dermatitis and asthma: A nationwide registry-based study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Chemicals in moisturizers may promote type 2 inflammation and food allergy

    Publikation: Bidrag til tidsskriftLetterForskningpeer review

  3. Nickel release from metallic earrings: A survey of the Danish market and validation of the nickel spot test

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

About 20% of the general population is contact-sensitized to common haptens such as fragrances, preservatives, and metals. Many also develop allergic contact dermatitis (ACD), the clinical manifestation of contact sensitization. ACD represents a common health issue and is also one of the most important occupational diseases. Although this inflammatory skin disease is mediated predominantly by memory T lymphocytes recognizing low-molecular-weight chemicals after skin contact, the innate immune system also plays an important role. Along that line, the presence of irritants may increase the risk of ACD and therefore ACD is often seen in the context of irritant contact dermatitis. In this review article, we discuss recent progress in basic research that has dramatically increased our understanding of the pathomechanisms of ACD and provides a basis for the development of novel diagnostic and therapeutic measures. Current methods for diagnosis as well as treatment options of ACD are also discussed.

StatusUdgivet - 2018

ID: 55201934