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Region Hovedstaden - en del af Københavns Universitetshospital
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Real-world evidence to guide healthcare policies in oncology

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

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Randomized controlled clinical trials (RCTs) in oncology enroll patients who meet strict protocol-specified criteria. Many of these criteria overlap across multiple RCTs. A vast proportion of patients with metastatic cancer do not meet such criteria. Hence, patient populations encountered in clinical practice are essentially different from RCT-populations, questioning the representativeness of these trials. A real-world evidence approach, using data from clinical practice, is increasingly employed to complement the information on drug safety and efficacy obtained from traditional clinical trials.

OriginalsprogEngelsk
TidsskriftOncotarget
Vol/bind10
Udgave nummer44
Sider (fra-til)4513-4515
Antal sider3
ISSN1949-2553
DOI
StatusUdgivet - 16 jul. 2019

ID: 57727604