Rare variants in GJA5 are associated with early-onset lone atrial fibrillation

Ingrid E Christophersen; Haya N Holmegard; Javad Jabbari; Ahmad Sajadieh; Stig Haunsø; Arnljot Tveit; Jesper H Svendsen; Morten S Olesen

doi:10.1016/j.cjca.2012.08.002

Rare variants in GJA5 are associated with early-onset lone atrial fibrillation

Ingrid E Christophersen
, Haya N Holmegard
, Javad Jabbari
, Ahmad Sajadieh
, Stig Haunsø
, Arnljot Tveit
, Jesper H Svendsen
, Morten S Olesen

Hjerteafdelingen BFH

48 Citationer (Scopus)

Abstract

Genetic factors are believed to be important in early-onset lone atrial fibrillation (AF). The gene GJA5 encodes the gap-junction protein Cx40, which together with Cx43 is responsible for the electrical coupling of the atrial cardiomyocytes. The regulatory single nucleotide polymorphism rs10465885 in GJA5 was recently associated with early-onset lone AF (

Originalsprog	Engelsk
Tidsskrift	The Canadian journal of cardiology
Vol/bind	29
Udgave nummer	1
Sider (fra-til)	111-6
Antal sider	6
ISSN	0828-282X
DOI	https://doi.org/10.1016/j.cjca.2012.08.002
Status	Udgivet - jan. 2013

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10.1016/j.cjca.2012.08.002

Citationsformater

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title = "Rare variants in GJA5 are associated with early-onset lone atrial fibrillation",

abstract = "Genetic factors are believed to be important in early-onset lone atrial fibrillation (AF). The gene GJA5 encodes the gap-junction protein Cx40, which together with Cx43 is responsible for the electrical coupling of the atrial cardiomyocytes. The regulatory single nucleotide polymorphism rs10465885 in GJA5 was recently associated with early-onset lone AF (",

keywords = "Adult, Age of Onset, Alleles, Atrial Fibrillation, Confidence Intervals, Connexins, Denmark, Female, Genetic Predisposition to Disease, Genetic Testing, Genotype, Heart Atria, Humans, Incidence, Male, Middle Aged, Norway, Odds Ratio, Polymorphism, Single Nucleotide, RNA, Messenger",

author = "Christophersen, \{Ingrid E\} and Holmegard, \{Haya N\} and Javad Jabbari and Ahmad Sajadieh and Stig Hauns{\o} and Arnljot Tveit and Svendsen, \{Jesper H\} and Olesen, \{Morten S\}",

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T1 - Rare variants in GJA5 are associated with early-onset lone atrial fibrillation

AU - Christophersen, Ingrid E

AU - Holmegard, Haya N

AU - Jabbari, Javad

AU - Sajadieh, Ahmad

AU - Haunsø, Stig

AU - Tveit, Arnljot

AU - Svendsen, Jesper H

AU - Olesen, Morten S

PY - 2013/1

Y1 - 2013/1

N2 - Genetic factors are believed to be important in early-onset lone atrial fibrillation (AF). The gene GJA5 encodes the gap-junction protein Cx40, which together with Cx43 is responsible for the electrical coupling of the atrial cardiomyocytes. The regulatory single nucleotide polymorphism rs10465885 in GJA5 was recently associated with early-onset lone AF (

AB - Genetic factors are believed to be important in early-onset lone atrial fibrillation (AF). The gene GJA5 encodes the gap-junction protein Cx40, which together with Cx43 is responsible for the electrical coupling of the atrial cardiomyocytes. The regulatory single nucleotide polymorphism rs10465885 in GJA5 was recently associated with early-onset lone AF (

KW - Adult

KW - Age of Onset

KW - Alleles

KW - Atrial Fibrillation

KW - Confidence Intervals

KW - Connexins

KW - Denmark

KW - Female

KW - Genetic Predisposition to Disease

KW - Genetic Testing

KW - Genotype

KW - Heart Atria

KW - Humans

KW - Incidence

KW - Male

KW - Middle Aged

KW - Norway

KW - Odds Ratio

KW - Polymorphism, Single Nucleotide

KW - RNA, Messenger

U2 - 10.1016/j.cjca.2012.08.002

DO - 10.1016/j.cjca.2012.08.002

M3 - Journal article

C2 - 23040431

SN - 0828-282X

VL - 29

SP - 111

EP - 116

JO - The Canadian journal of cardiology

JF - The Canadian journal of cardiology

IS - 1

ER -

Rare variants in GJA5 are associated with early-onset lone atrial fibrillation

Abstract

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