Rare variants in GJA5 are associated with early-onset lone atrial fibrillation

Ingrid E Christophersen, Haya N Holmegard, Javad Jabbari, Ahmad Sajadieh, Stig Haunsø, Arnljot Tveit, Jesper H Svendsen, Morten S Olesen

45 Citationer (Scopus)

Abstract

Genetic factors are believed to be important in early-onset lone atrial fibrillation (AF). The gene GJA5 encodes the gap-junction protein Cx40, which together with Cx43 is responsible for the electrical coupling of the atrial cardiomyocytes. The regulatory single nucleotide polymorphism rs10465885 in GJA5 was recently associated with early-onset lone AF (
OriginalsprogEngelsk
TidsskriftThe Canadian journal of cardiology
Vol/bind29
Udgave nummer1
Sider (fra-til)111-6
Antal sider6
ISSN0828-282X
DOI
StatusUdgivet - jan. 2013

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