Rare non-coding Desmoglein-2 variant contributes to Arrhythmogenic right ventricular cardiomyopathy

Keyphrases

• Non-coding 100%
• Arrhythmogenic Right Ventricular Cardiomyopathy 100%
• Desmoglein 100%
• Protein Level 20%
• Myocardial Biopsy 20%
• Healthy Controls 10%
• Binding Site 10%
• Coding Sequence 10%
• Genetic Analysis 10%
• Promoter Activity 10%
• Co-segregation 10%
• Publicly Available 10%
• Activator protein-1 (AP-1) 10%
• Immunohistochemical Analysis 10%
• Transcriptional Activity 10%
• Population Frequency 10%
• Frequency Analysis 10%
• Reporter Gene Assay 10%
• Chromatin Immunoprecipitation (ChIP) 10%
• Potential Contribution 10%
• Upstream Region 10%
• Electrophoretic Mobility Shift Assay 10%
• Transcription in Vitro 10%
• Desmosomal Genes 10%
• In Silico Tools 10%
• Luciferase Reporter Assay 10%

Biochemistry, Genetics and Molecular Biology

• Desmoglein-2 100%
• Allele 20%
• Reporter Gene 20%
• Population 10%
• Binding Site 10%
• Genetics 10%
• Computer Model 10%
• Promoter Region 10%
• Transcription 10%
• Synapsin I 10%
• Luciferase 10%
• Chromatin Immunoprecipitation 10%
• Electrophoretic Mobility Shift Assay 10%