Randomized trial: immunogenicity and safety of coadministered human papillomavirus-16/18 AS04-adjuvanted vaccine and combined hepatitis A and B vaccine in girls

Court Pedersen, Morten Breindahl, Naresh Aggarwal, Johan Berglund, György Oroszlán, Sven Arne Silfverdal, Péter Szüts, Michael O'Mahony, Marie-Pierre David, Kurt Dobbelaere, Gary Dubin, Dominique Descamps

29 Citationer (Scopus)

Abstract

This randomized, open, controlled, multicenter study (110886/NCT00578227) evaluated human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine (HPV-16/18 vaccine) coadministered with inactivated hepatitis A and B (HAB) vaccine. Coprimary objectives were to demonstrate noninferiority of hepatitis A, hepatitis B, and HPV-16/18 immune responses at month 7 when vaccines were coadministered, compared with the same vaccines administered alone.
OriginalsprogEngelsk
TidsskriftJournal of Adolescent Health
Vol/bind50
Udgave nummer1
Sider (fra-til)38-46
Antal sider9
ISSN1054-139X
DOI
StatusUdgivet - 2012

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