Randomized controlled trial on collagen/oxidized regenerated cellulose/silver treatment

Finn Gottrup; Breda Mary Cullen; Tonny Karlsmark; Morten Bischoff-Mikkelsen; Lorraine Nisbet; Molly Camilla Gibson

doi:10.1111/wrr.12020

Randomized controlled trial on collagen/oxidized regenerated cellulose/silver treatment

Finn Gottrup
, Breda Mary Cullen
, Tonny Karlsmark
, Morten Bischoff-Mikkelsen
, Lorraine Nisbet
, Molly Camilla Gibson

Dermatologisk og Venerologisk Afdeling og Videncenter for Sårheling BFH

82 Citationer (Scopus)

Abstract

Collagen/oxidized regenerated cellulose (ORC)/silver therapy has been designed to facilitate wound healing by normalizing the microenvironment and correcting biochemical imbalances in chronic wounds. The aim of this study was to compare collagen/ORC/silver therapy to control (standard treatment). Patients with diabetic foot ulcers were randomized to either collagen/ORC/silver (24) or control treatment (15). Wound area measurements and wound fluid samples were taken weekly. Protease levels were measured in wound fluid samples to investigate differences between responders (≥50% reduction in wound area by week 4) and nonresponders (

Originalsprog	Engelsk
Tidsskrift	Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
Vol/bind	21
Udgave nummer	2
Sider (fra-til)	216-25
Antal sider	10
ISSN	1067-1927
DOI	https://doi.org/10.1111/wrr.12020
Status	Udgivet - 2014

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10.1111/wrr.12020

Citationsformater

Randomized controlled trial on collagen/oxidized regenerated cellulose/silver treatment. / Gottrup, Finn; Cullen, Breda Mary; Karlsmark, Tonny et al.
I: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, Bind 21, Nr. 2, 2014, s. 216-25.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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abstract = "Collagen/oxidized regenerated cellulose (ORC)/silver therapy has been designed to facilitate wound healing by normalizing the microenvironment and correcting biochemical imbalances in chronic wounds. The aim of this study was to compare collagen/ORC/silver therapy to control (standard treatment). Patients with diabetic foot ulcers were randomized to either collagen/ORC/silver (24) or control treatment (15). Wound area measurements and wound fluid samples were taken weekly. Protease levels were measured in wound fluid samples to investigate differences between responders (≥50\% reduction in wound area by week 4) and nonresponders (",

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author = "Finn Gottrup and Cullen, \{Breda Mary\} and Tonny Karlsmark and Morten Bischoff-Mikkelsen and Lorraine Nisbet and Gibson, \{Molly Camilla\}",

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doi = "10.1111/wrr.12020",

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AU - Cullen, Breda Mary

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AU - Nisbet, Lorraine

AU - Gibson, Molly Camilla

PY - 2014

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AB - Collagen/oxidized regenerated cellulose (ORC)/silver therapy has been designed to facilitate wound healing by normalizing the microenvironment and correcting biochemical imbalances in chronic wounds. The aim of this study was to compare collagen/ORC/silver therapy to control (standard treatment). Patients with diabetic foot ulcers were randomized to either collagen/ORC/silver (24) or control treatment (15). Wound area measurements and wound fluid samples were taken weekly. Protease levels were measured in wound fluid samples to investigate differences between responders (≥50% reduction in wound area by week 4) and nonresponders (

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KW - Aged, 80 and over

KW - Bandages

KW - Biological Markers

KW - Cellulose, Oxidized

KW - Collagen

KW - Diabetic Foot

KW - Exudates and Transudates

KW - Female

KW - Fibrin Foam

KW - Humans

KW - Inflammation

KW - Male

KW - Matrix Metalloproteinase 1

KW - Matrix Metalloproteinase 9

KW - Middle Aged

KW - Pancreatic Elastase

KW - Silver

KW - Treatment Outcome

KW - Wound Healing

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Randomized controlled trial on collagen/oxidized regenerated cellulose/silver treatment

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