Randomized and double-blinded pilot clinical study of the safety and anti-diabetic efficacy of the Rauvolfia-Citrus tea, as used in Nigerian traditional medicine

Joan I A Campbell-Tofte; Per Mølgaard; Knud Josefsen; Zostam Yasin Abdallah; Steen Honoré Hansen; Claus Cornett; Huiling Mu; Erik A Richter; Henning Willads Petersen; Jens Christian Nørregaard; Kaj Winther

doi:10.1016/j.jep.2010.10.013

Randomized and double-blinded pilot clinical study of the safety and anti-diabetic efficacy of the Rauvolfia-Citrus tea, as used in Nigerian traditional medicine

Joan I A Campbell-Tofte, Per Mølgaard, Knud Josefsen, Zostam Yasin Abdallah, Steen Honoré Hansen, Claus Cornett, Huiling Mu, Erik A Richter, Henning Willads Petersen, Jens Christian Nørregaard, Kaj Winther

28 Citationer (Scopus)

Abstract

The aim of this randomized and double blinded pilot clinical trial was to investigate the anti-diabetic efficacy of the Rauvolfia-Citrus (RC) tea in humans. We have earlier shown that a combination of calorie-restriction and chronic administration of the RC tea to the genetic diabetic (BKS-db) mice resulted in the normalization of blood sugar, reduction in lipid accumulated in the mice eyes and prevention of the degeneration of the otherwise brittle BKS-db pancreas. The tea is made by boiling foliage of Rauvolfia vomitoria and fruits of Citrus aurantium and is used to treat diabetes in Nigerian folk medicine.

Originalsprog	Engelsk
Tidsskrift	Journal of Ethnopharmacology
Vol/bind	133
Udgave nummer	2
Sider (fra-til)	402-11
Antal sider	10
ISSN	0378-8741
DOI	https://doi.org/10.1016/j.jep.2010.10.013
Status	Udgivet - 27 jan. 2011

Adgang til dokumentet

10.1016/j.jep.2010.10.013

Citationsformater

Campbell-Tofte, J. I. A., Mølgaard, P., Josefsen, K., Abdallah, Z. Y., Hansen, S. H., Cornett, C., Mu, H., Richter, E. A., Petersen, H. W., Nørregaard, J. C., & Winther, K. (2011). Randomized and double-blinded pilot clinical study of the safety and anti-diabetic efficacy of the Rauvolfia-Citrus tea, as used in Nigerian traditional medicine. Journal of Ethnopharmacology, 133(2), 402-11. https://doi.org/10.1016/j.jep.2010.10.013

Randomized and double-blinded pilot clinical study of the safety and anti-diabetic efficacy of the Rauvolfia-Citrus tea, as used in Nigerian traditional medicine. / Campbell-Tofte, Joan I A; Mølgaard, Per; Josefsen, Knud et al.
I: Journal of Ethnopharmacology, Bind 133, Nr. 2, 27.01.2011, s. 402-11.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Campbell-Tofte, JIA, Mølgaard, P, Josefsen, K, Abdallah, ZY, Hansen, SH, Cornett, C, Mu, H, Richter, EA, Petersen, HW, Nørregaard, JC & Winther, K 2011, 'Randomized and double-blinded pilot clinical study of the safety and anti-diabetic efficacy of the Rauvolfia-Citrus tea, as used in Nigerian traditional medicine', Journal of Ethnopharmacology, bind 133, nr. 2, s. 402-11. https://doi.org/10.1016/j.jep.2010.10.013

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abstract = "The aim of this randomized and double blinded pilot clinical trial was to investigate the anti-diabetic efficacy of the Rauvolfia-Citrus (RC) tea in humans. We have earlier shown that a combination of calorie-restriction and chronic administration of the RC tea to the genetic diabetic (BKS-db) mice resulted in the normalization of blood sugar, reduction in lipid accumulated in the mice eyes and prevention of the degeneration of the otherwise brittle BKS-db pancreas. The tea is made by boiling foliage of Rauvolfia vomitoria and fruits of Citrus aurantium and is used to treat diabetes in Nigerian folk medicine.",

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AU - Abdallah, Zostam Yasin

AU - Hansen, Steen Honoré

AU - Cornett, Claus

AU - Mu, Huiling

AU - Richter, Erik A

AU - Petersen, Henning Willads

AU - Nørregaard, Jens Christian

AU - Winther, Kaj

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Randomized and double-blinded pilot clinical study of the safety and anti-diabetic efficacy of the Rauvolfia-Citrus tea, as used in Nigerian traditional medicine

Abstract

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