Randomized and double-blinded pilot clinical study of the safety and anti-diabetic efficacy of the Rauvolfia-Citrus tea, as used in Nigerian traditional medicine

Joan I A Campbell-Tofte, Per Mølgaard, Knud Josefsen, Zostam Yasin Abdallah, Steen Honoré Hansen, Claus Cornett, Huiling Mu, Erik A Richter, Henning Willads Petersen, Jens Christian Nørregaard, Kaj Winther

22 Citationer (Scopus)

Abstract

The aim of this randomized and double blinded pilot clinical trial was to investigate the anti-diabetic efficacy of the Rauvolfia-Citrus (RC) tea in humans. We have earlier shown that a combination of calorie-restriction and chronic administration of the RC tea to the genetic diabetic (BKS-db) mice resulted in the normalization of blood sugar, reduction in lipid accumulated in the mice eyes and prevention of the degeneration of the otherwise brittle BKS-db pancreas. The tea is made by boiling foliage of Rauvolfia vomitoria and fruits of Citrus aurantium and is used to treat diabetes in Nigerian folk medicine.
OriginalsprogEngelsk
TidsskriftJournal of Ethnopharmacology
Vol/bind133
Udgave nummer2
Sider (fra-til)402-11
Antal sider10
ISSN0378-8741
DOI
StatusUdgivet - 27 jan. 2011

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