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Region Hovedstaden - en del af Københavns Universitetshospital
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Radical prostatectomy versus expectant treatment for early carcinoma of the prostate. Twenty-three year follow-up of a prospective randomized study

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  1. Prostate cancer in Denmark. Incidence, morbidity and mortality

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  2. Serum testosterone as a prognostic factor in patients with advanced prostatic carcinoma

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  3. Carcinoma of the prostate. Classification

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  4. Carcinoma of the prostate. Early diagnosis--screening

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  5. Carcinoma of the prostate. Prognostic factors

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  1. Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

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  2. Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants

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Vis graf over relationer
In a study by the Veterans Administration Cooperative Urological Research Group (VACURG), 142 patients with localized prostate cancer, VACURG stage I and II, were randomized between radical prostatectomy plus placebo versus placebo alone as initial treatment. 111 patients were evaluable for treatment comparison. Median follow-up for survival is 23 years. The prognostic value of Gleason histologic grading was confirmed. A difference in overall survival in favor of radical prostatectomy was observed in stage I patients. However, after adjustment for imbalance in age distribution, no statistically significant differences in survival could be demonstrated in either stage or in both stages combined. The results are discussed considering the small sample size and the limited statistical power of the study.
OriginalsprogEngelsk
BogserieScandinavian Journal of Urology and Nephrology. Supplement
Vol/bind172
Sider (fra-til)65-72
Antal sider8
ISSN0300-8886
StatusUdgivet - 1995

ID: 36731112