TY - JOUR
T1 - Quantitative echocardiographic analysis of the right ventricle in healthy individuals
AU - Kjaergaard, Jesper
AU - Sogaard, Peter
AU - Hassager, Christian
PY - 2006/11
Y1 - 2006/11
N2 - INTRODUCTION: Three-dimensional echocardiography and Doppler tissue imaging (DTI) are new technologies for evaluation of right ventricular (RV) size and function, but little is known about the differences of these measurements in men and women of different age groups, and how these differences can be adjusted.METHODS: In all, 54 healthy participants, mean age 59 years (range: 21-86), underwent resting echocardiography, including 3-dimensional echocardiography and DTI.RESULTS: There were significant differences in RV end-diastolic volume between men and women (129 +/- 25 vs 102 +/- 33 mL, P < .01). Adjusting to lean body mass, but not the body surface area or height, eliminated this difference (2.1 +/- 0.5 vs 2.2 +/- 0.4 mL/kg, P = not significant). DTI demonstrated that RV time to peak systolic velocity, late diastolic basal velocity, and peak systolic strain were significantly affected by increasing age (r = -0.53, P < .0001; r = 0.58, P < .0001; and r = -0.35, P < .05, respectively).CONCLUSION: Echocardiographic measures of RV size are significantly different in men and women, and indexing to lean body mass appears to be more effective than indexing to body surface area. DTI is feasible, but the amount of variation found in the measurements may be a limiting factor in the clinical application of the technology.
AB - INTRODUCTION: Three-dimensional echocardiography and Doppler tissue imaging (DTI) are new technologies for evaluation of right ventricular (RV) size and function, but little is known about the differences of these measurements in men and women of different age groups, and how these differences can be adjusted.METHODS: In all, 54 healthy participants, mean age 59 years (range: 21-86), underwent resting echocardiography, including 3-dimensional echocardiography and DTI.RESULTS: There were significant differences in RV end-diastolic volume between men and women (129 +/- 25 vs 102 +/- 33 mL, P < .01). Adjusting to lean body mass, but not the body surface area or height, eliminated this difference (2.1 +/- 0.5 vs 2.2 +/- 0.4 mL/kg, P = not significant). DTI demonstrated that RV time to peak systolic velocity, late diastolic basal velocity, and peak systolic strain were significantly affected by increasing age (r = -0.53, P < .0001; r = 0.58, P < .0001; and r = -0.35, P < .05, respectively).CONCLUSION: Echocardiographic measures of RV size are significantly different in men and women, and indexing to lean body mass appears to be more effective than indexing to body surface area. DTI is feasible, but the amount of variation found in the measurements may be a limiting factor in the clinical application of the technology.
KW - Echocardiography, Doppler/methods
KW - Echocardiography, Three-Dimensional/methods
KW - Feasibility Studies
KW - Female
KW - Heart Ventricles/diagnostic imaging
KW - Humans
KW - Image Enhancement/methods
KW - Image Interpretation, Computer-Assisted/methods
KW - Male
KW - Middle Aged
KW - Reference Values
KW - Reproducibility of Results
KW - Sensitivity and Specificity
KW - Stroke Volume
KW - Ventricular Function, Right
U2 - 10.1016/j.echo.2006.05.012
DO - 10.1016/j.echo.2006.05.012
M3 - Journal article
C2 - 17098140
SN - 0894-7317
VL - 19
SP - 1365
EP - 1372
JO - Journal of the American Society of Echocardiography
JF - Journal of the American Society of Echocardiography
IS - 11
ER -