@article{9d84b672243e48589809bdaf9b2f025c,
title = "Quantitative cell-free DNA, KRAS, and BRAF mutations in plasma from patients with metastatic colorectal cancer during treatment with cetuximab and irinotecan",
abstract = "The present study investigated the levels of circulating cell-free DNA (cfDNA) in plasma from patients with metastatic colorectal cancer (mCRC) in relation to third-line treatment with cetuximab and irinotecan and the quantitative relationship of cfDNA with tumor-specific mutations in plasma.",
keywords = "Adult, Aged, Aged, 80 and over, Alleles, Antibodies, Monoclonal, Antineoplastic Combined Chemotherapy Protocols, Camptothecin, Colorectal Neoplasms, DNA, Neoplasm, Female, Humans, Male, Middle Aged, Mutation, Neoplasm Metastasis, Prognosis, Proto-Oncogene Proteins, Proto-Oncogene Proteins B-raf, Treatment Outcome, ras Proteins",
author = "Spindler, {Karen-Lise Garm} and Niels Pallisgaard and Ivan Vogelius and Jakobsen, {Leif Anders}",
note = "{\textcopyright}2012 AACR.",
year = "2012",
doi = "10.1158/1078-0432.CCR-11-0564",
language = "English",
volume = "18",
pages = "1177--85",
journal = "Clinical Cancer Research",
issn = "1078-0432",
publisher = "American Association for Cancer Research (A A C R)",
number = "4",
}