Quantification of liver fat using magnetic resonance spectroscopy.

Bidragets oversatte titel: Quantification of liver fat using magnetic resonance spectroscopy.

C Thomsen, Povl Ulrik Becker, K Winkler, P Christoffersen, M Jensen, O Henriksen

309 Citationer (Scopus)

Abstract

Localized proton MR spectroscopy using stimulated echoes was used to quantify the liver fat concentration in patients with various degrees of fatty liver due to alcohol abuse. Ten patients underwent a liver biopsy followed by chemical triglyceride estimation of the fatty content. A statistically significant correlation was found between the fat concentration measured in the liver biopsies, and the concentration calculated from the spectroscopic experiments (r = 0.9, p < .001). Quantitative assessment of liver fat concentrations using localized spectroscopy is superior to methods based on differences in relaxation times, and can be used to estimate the fat concentration over the full range of fat content in contrast to the spectroscopic imaging methods. Localized spectroscopy may replace liver biopsy in the diagnosis of diffuse fatty infiltrations, and can be used for follow-up, due to its noninvasive nature.
Bidragets oversatte titelQuantification of liver fat using magnetic resonance spectroscopy.
OriginalsprogEngelsk
TidsskriftMagnetic Resonance Imaging
Vol/bind12
Udgave nummer3
Sider (fra-til)487-495
Antal sider9
ISSN0730-725X
StatusUdgivet - 1994

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