Abstrakt
In-vivo Manganese-Enhanced MRI (MEMRI) studies have shown important potential in rodents for the delineation of cytoarchitectural brain features and of functional details. Ex-vivo MEMRI on the other hand offers the possibility to investigate brain microstructure and function with improved spatial resolution and no motion artefacts. Here, ex-vivo lamb brains were immersed in a highly concentrated MnCl2 solution for a month and revealed interesting cytoarchitectural features already 24 hours after immersion and up to 3 months after the end of immersion on MPRAGE images at 3T. A novel ex-vivo MEMRI approach is proposed, which could benefit MEMRI translation to human studies.
| Originalsprog | Engelsk |
|---|---|
| Publikationsdato | 11 maj 2022 |
| Status | Udgivet - 11 maj 2022 |
| Begivenhed | Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting - London, Englnd, UK Varighed: 7 maj 2022 → 12 maj 2022 https://www.ismrm.org/22m/ |
Konference
| Konference | Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting |
|---|---|
| Lokation | London, Englnd, UK |
| Periode | 07/05/2022 → 12/05/2022 |
| Internetadresse |