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Psychotic-like experiences in pre-adolescence: what precedes the antecedent symptoms of severe mental illness?

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Harvard

Bolhuis, K, Koopman-Verhoeff, ME, Blanken, LME, Cibrev, D, Jaddoe, VWV, Verhulst, FC, Hillegers, MHJ, Kushner, SA & Tiemeier, H 2018, 'Psychotic-like experiences in pre-adolescence: what precedes the antecedent symptoms of severe mental illness?' Acta Psychiatrica Scandinavica, bind 138, nr. 1, s. 15-25. https://doi.org/10.1111/acps.12891

APA

Bolhuis, K., Koopman-Verhoeff, M. E., Blanken, L. M. E., Cibrev, D., Jaddoe, V. W. V., Verhulst, F. C., ... Tiemeier, H. (2018). Psychotic-like experiences in pre-adolescence: what precedes the antecedent symptoms of severe mental illness? Acta Psychiatrica Scandinavica, 138(1), 15-25. https://doi.org/10.1111/acps.12891

CBE

Bolhuis K, Koopman-Verhoeff ME, Blanken LME, Cibrev D, Jaddoe VWV, Verhulst FC, Hillegers MHJ, Kushner SA, Tiemeier H. 2018. Psychotic-like experiences in pre-adolescence: what precedes the antecedent symptoms of severe mental illness?. Acta Psychiatrica Scandinavica. 138(1):15-25. https://doi.org/10.1111/acps.12891

MLA

Vancouver

Author

Bolhuis, K ; Koopman-Verhoeff, M E ; Blanken, L M E ; Cibrev, D ; Jaddoe, V W V ; Verhulst, F C ; Hillegers, M H J ; Kushner, S A ; Tiemeier, H. / Psychotic-like experiences in pre-adolescence : what precedes the antecedent symptoms of severe mental illness?. I: Acta Psychiatrica Scandinavica. 2018 ; Bind 138, Nr. 1. s. 15-25.

Bibtex

@article{dbbbda9aee8744f4a29aead51f42c8ed,
title = "Psychotic-like experiences in pre-adolescence: what precedes the antecedent symptoms of severe mental illness?",
abstract = "OBJECTIVE: Adolescent psychotic-like experiences predict the onset of psychosis, but also predict subsequent non-psychotic disorders. Therefore, it is crucial to better understand the aetiology of psychotic-like experiences. This study examined whether (a) child emotional and behavioural problems at 3 and 6 years, or (b) childhood adversities were associated with psychotic-like experiences at age 10 years.METHOD: This prospective study was embedded in the Generation R Study; 3984 children (mean age 10 years) completed a psychotic-like experiences questionnaire. Mothers reported problems of their child at ages 3, 6 and 10 years. Additionally, mothers were interviewed about their child's adversities.RESULTS: Psychotic-like experiences were endorsed by ~20{\%} of children and predicted by both emotional and behavioural problems at 3 years (e.g. emotional-reactive problems: ORadjusted = 1.10, 95{\%} CI: 1.06-1.15, aggressive behaviour: ORadjusted = 1.03, 95{\%} CI: 1.02-1.05) and 6 years (e.g. anxious/depressed problems: ORadjusted = 1.11, 95{\%} CI: 1.06-1.15, aggressive behaviour: ORadjusted = 1.04, 95{\%} CI: 1.04-1.05). Childhood adversities were associated with psychotic-like experiences (>2 adversities: ORadjusted = 2.24, 95{\%} CI: 1.72-2.92), which remained significant after adjustment for comorbid psychiatric problems.CONCLUSION: This study demonstrated associations between early adversities, childhood emotional and behavioural problems and pre-adolescent psychotic-like experiences, which will improve the understanding of children at increased risk of severe mental illness.",
author = "K Bolhuis and Koopman-Verhoeff, {M E} and Blanken, {L M E} and D Cibrev and Jaddoe, {V W V} and Verhulst, {F C} and Hillegers, {M H J} and Kushner, {S A} and H Tiemeier",
note = "{\circledC} 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.",
year = "2018",
month = "7",
doi = "10.1111/acps.12891",
language = "English",
volume = "138",
pages = "15--25",
journal = "Acta Psychiatrica Scandinavica",
issn = "0001-690X",
publisher = "Wiley-Blackwell Publishing Ltd",
number = "1",

}

RIS

TY - JOUR

T1 - Psychotic-like experiences in pre-adolescence

T2 - what precedes the antecedent symptoms of severe mental illness?

AU - Bolhuis, K

AU - Koopman-Verhoeff, M E

AU - Blanken, L M E

AU - Cibrev, D

AU - Jaddoe, V W V

AU - Verhulst, F C

AU - Hillegers, M H J

AU - Kushner, S A

AU - Tiemeier, H

N1 - © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

PY - 2018/7

Y1 - 2018/7

N2 - OBJECTIVE: Adolescent psychotic-like experiences predict the onset of psychosis, but also predict subsequent non-psychotic disorders. Therefore, it is crucial to better understand the aetiology of psychotic-like experiences. This study examined whether (a) child emotional and behavioural problems at 3 and 6 years, or (b) childhood adversities were associated with psychotic-like experiences at age 10 years.METHOD: This prospective study was embedded in the Generation R Study; 3984 children (mean age 10 years) completed a psychotic-like experiences questionnaire. Mothers reported problems of their child at ages 3, 6 and 10 years. Additionally, mothers were interviewed about their child's adversities.RESULTS: Psychotic-like experiences were endorsed by ~20% of children and predicted by both emotional and behavioural problems at 3 years (e.g. emotional-reactive problems: ORadjusted = 1.10, 95% CI: 1.06-1.15, aggressive behaviour: ORadjusted = 1.03, 95% CI: 1.02-1.05) and 6 years (e.g. anxious/depressed problems: ORadjusted = 1.11, 95% CI: 1.06-1.15, aggressive behaviour: ORadjusted = 1.04, 95% CI: 1.04-1.05). Childhood adversities were associated with psychotic-like experiences (>2 adversities: ORadjusted = 2.24, 95% CI: 1.72-2.92), which remained significant after adjustment for comorbid psychiatric problems.CONCLUSION: This study demonstrated associations between early adversities, childhood emotional and behavioural problems and pre-adolescent psychotic-like experiences, which will improve the understanding of children at increased risk of severe mental illness.

AB - OBJECTIVE: Adolescent psychotic-like experiences predict the onset of psychosis, but also predict subsequent non-psychotic disorders. Therefore, it is crucial to better understand the aetiology of psychotic-like experiences. This study examined whether (a) child emotional and behavioural problems at 3 and 6 years, or (b) childhood adversities were associated with psychotic-like experiences at age 10 years.METHOD: This prospective study was embedded in the Generation R Study; 3984 children (mean age 10 years) completed a psychotic-like experiences questionnaire. Mothers reported problems of their child at ages 3, 6 and 10 years. Additionally, mothers were interviewed about their child's adversities.RESULTS: Psychotic-like experiences were endorsed by ~20% of children and predicted by both emotional and behavioural problems at 3 years (e.g. emotional-reactive problems: ORadjusted = 1.10, 95% CI: 1.06-1.15, aggressive behaviour: ORadjusted = 1.03, 95% CI: 1.02-1.05) and 6 years (e.g. anxious/depressed problems: ORadjusted = 1.11, 95% CI: 1.06-1.15, aggressive behaviour: ORadjusted = 1.04, 95% CI: 1.04-1.05). Childhood adversities were associated with psychotic-like experiences (>2 adversities: ORadjusted = 2.24, 95% CI: 1.72-2.92), which remained significant after adjustment for comorbid psychiatric problems.CONCLUSION: This study demonstrated associations between early adversities, childhood emotional and behavioural problems and pre-adolescent psychotic-like experiences, which will improve the understanding of children at increased risk of severe mental illness.

U2 - 10.1111/acps.12891

DO - 10.1111/acps.12891

M3 - Journal article

VL - 138

SP - 15

EP - 25

JO - Acta Psychiatrica Scandinavica

JF - Acta Psychiatrica Scandinavica

SN - 0001-690X

IS - 1

ER -

ID: 56204337