TY - JOUR
T1 - Psychiatric morbidity among men using anabolic steroids
AU - Windfeld-Mathiasen, Josefine
AU - Christoffersen, Thea
AU - Strand, Niels August Willer
AU - Dalhoff, Kim
AU - Andersen, Jon Traerup
AU - Horwitz, Henrik
N1 - © 2022 The Authors. Depression and Anxiety published by Wiley Periodicals LLC.
PY - 2022/10/25
Y1 - 2022/10/25
N2 - OBJECTIVE: The purpose of this study was to investigate the psychiatric morbidity among men with abuse of anabolic steroids.METHODS: The design is a retrospectively matched cohort study. Five hundred and fourty-five males, who tested positive for anabolic steroids in Danish fitness centers during the period January 3, 2006 to March 1, 2018, were matched with 5450 randomly chosen male controls. Data was cross-referenced with seven national registers pertaining to information about education, employment status, and psychiatric comorbidity. Main outcomes and measures were prescription of psychopharmacological treatment.RESULTS: The incidence of treatment with anxiolytics (HR: 2.34, 95% CI: 1.62-3.38) and antipsychotics (HR: 2.69, 95% CI: 1.99-3.63) displayed a remarkable increase in the years following doping sanction, compared to the control group. The prevalence of antidepressant use was already markedly elevated several years before doping sanction, but also displayed a higher incidence in the years following sanction (HR: 1.65, 95% CI: 1.28-2.13). The associations remained highly significant after controlling for socioeconomic factors.CONCLUSION: Anabolic steroids use is strongly associated with psychiatric morbidity.
AB - OBJECTIVE: The purpose of this study was to investigate the psychiatric morbidity among men with abuse of anabolic steroids.METHODS: The design is a retrospectively matched cohort study. Five hundred and fourty-five males, who tested positive for anabolic steroids in Danish fitness centers during the period January 3, 2006 to March 1, 2018, were matched with 5450 randomly chosen male controls. Data was cross-referenced with seven national registers pertaining to information about education, employment status, and psychiatric comorbidity. Main outcomes and measures were prescription of psychopharmacological treatment.RESULTS: The incidence of treatment with anxiolytics (HR: 2.34, 95% CI: 1.62-3.38) and antipsychotics (HR: 2.69, 95% CI: 1.99-3.63) displayed a remarkable increase in the years following doping sanction, compared to the control group. The prevalence of antidepressant use was already markedly elevated several years before doping sanction, but also displayed a higher incidence in the years following sanction (HR: 1.65, 95% CI: 1.28-2.13). The associations remained highly significant after controlling for socioeconomic factors.CONCLUSION: Anabolic steroids use is strongly associated with psychiatric morbidity.
KW - Anabolic Agents/adverse effects
KW - Cohort Studies
KW - Humans
KW - Incidence
KW - Male
KW - Retrospective Studies
KW - Testosterone Congeners/adverse effects
UR - http://www.scopus.com/inward/record.url?scp=85140378286&partnerID=8YFLogxK
U2 - 10.1002/da.23287
DO - 10.1002/da.23287
M3 - Journal article
C2 - 36281632
SN - 1091-4269
VL - 39
SP - 805
EP - 812
JO - Depression and Anxiety
JF - Depression and Anxiety
IS - 12
ER -