Promoter polymorphism -119C/G in MYG1 (C12orf10) gene is related to vitiligo susceptibility and Arg4Gln affects mitochondrial entrance of Myg1

Mari-Anne Philips; Külli Kingo; Maire Karelson; Ranno Rätsep; Eerik Aunin; Ene Reimann; Paula Reemann; Orm Porosaar; Jonas Vikeså; Finn C Nielsen; Eero Vasar; Helgi Silm; Sulev Kõks

doi:10.1186/1471-2350-11-56

Promoter polymorphism -119C/G in MYG1 (C12orf10) gene is related to vitiligo susceptibility and Arg4Gln affects mitochondrial entrance of Myg1

Mari-Anne Philips
, Külli Kingo
, Maire Karelson
, Ranno Rätsep
, Eerik Aunin
, Ene Reimann
, Paula Reemann
, Orm Porosaar
, Jonas Vikeså
, Finn C Nielsen
, Eero Vasar
, Helgi Silm
, Sulev Kõks

Afdeling for Klinisk Biokemi DIA

15 Citationer (Scopus)

Abstract

MYG1 (Melanocyte proliferating gene 1, also C12orf10 in human) is a ubiquitous nucleo-mitochondrial protein, involved in early developmental processes and in adult stress/illness conditions. We recently showed that MYG1 mRNA expression is elevated in the skin of vitiligo patients. Our aim was to examine nine known polymorphisms in the MYG1 gene, to investigate their functionality, and to study their association with vitiligo susceptibility.

Originalsprog	Engelsk
Tidsskrift	B M C Medical Genetics
Vol/bind	11
Sider (fra-til)	56
ISSN	1471-2350
DOI	https://doi.org/10.1186/1471-2350-11-56
Status	Udgivet - 1 jan. 2010

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10.1186/1471-2350-11-56

Citationsformater

Philips, M.-A., Kingo, K., Karelson, M., Rätsep, R., Aunin, E., Reimann, E., Reemann, P., Porosaar, O., Vikeså, J., Nielsen, F. C., Vasar, E., Silm, H., & Kõks, S. (2010). Promoter polymorphism -119C/G in MYG1 (C12orf10) gene is related to vitiligo susceptibility and Arg4Gln affects mitochondrial entrance of Myg1. B M C Medical Genetics, 11, 56. https://doi.org/10.1186/1471-2350-11-56

Philips, M-A, Kingo, K, Karelson, M, Rätsep, R, Aunin, E, Reimann, E, Reemann, P, Porosaar, O, Vikeså, J, Nielsen, FC, Vasar, E, Silm, H & Kõks, S 2010, 'Promoter polymorphism -119C/G in MYG1 (C12orf10) gene is related to vitiligo susceptibility and Arg4Gln affects mitochondrial entrance of Myg1', B M C Medical Genetics, bind 11, s. 56. https://doi.org/10.1186/1471-2350-11-56

@article{a483c53d97f242b4995a854083d02bdb,

title = "Promoter polymorphism -119C/G in MYG1 (C12orf10) gene is related to vitiligo susceptibility and Arg4Gln affects mitochondrial entrance of Myg1",

abstract = "MYG1 (Melanocyte proliferating gene 1, also C12orf10 in human) is a ubiquitous nucleo-mitochondrial protein, involved in early developmental processes and in adult stress/illness conditions. We recently showed that MYG1 mRNA expression is elevated in the skin of vitiligo patients. Our aim was to examine nine known polymorphisms in the MYG1 gene, to investigate their functionality, and to study their association with vitiligo susceptibility.",

author = "Mari-Anne Philips and K{\"u}lli Kingo and Maire Karelson and Ranno R{\"a}tsep and Eerik Aunin and Ene Reimann and Paula Reemann and Orm Porosaar and Jonas Vikes{\aa} and Nielsen, \{Finn C\} and Eero Vasar and Helgi Silm and Sulev K{\~o}ks",

year = "2010",

month = jan,

day = "1",

doi = "10.1186/1471-2350-11-56",

language = "English",

volume = "11",

pages = "56",

journal = "B M C Medical Genetics",

issn = "1471-2350",

publisher = "BioMed Central Ltd",

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TY - JOUR

T1 - Promoter polymorphism -119C/G in MYG1 (C12orf10) gene is related to vitiligo susceptibility and Arg4Gln affects mitochondrial entrance of Myg1

AU - Philips, Mari-Anne

AU - Kingo, Külli

AU - Karelson, Maire

AU - Rätsep, Ranno

AU - Aunin, Eerik

AU - Reimann, Ene

AU - Reemann, Paula

AU - Porosaar, Orm

AU - Vikeså, Jonas

AU - Nielsen, Finn C

AU - Vasar, Eero

AU - Silm, Helgi

AU - Kõks, Sulev

PY - 2010/1/1

Y1 - 2010/1/1

N2 - MYG1 (Melanocyte proliferating gene 1, also C12orf10 in human) is a ubiquitous nucleo-mitochondrial protein, involved in early developmental processes and in adult stress/illness conditions. We recently showed that MYG1 mRNA expression is elevated in the skin of vitiligo patients. Our aim was to examine nine known polymorphisms in the MYG1 gene, to investigate their functionality, and to study their association with vitiligo susceptibility.

AB - MYG1 (Melanocyte proliferating gene 1, also C12orf10 in human) is a ubiquitous nucleo-mitochondrial protein, involved in early developmental processes and in adult stress/illness conditions. We recently showed that MYG1 mRNA expression is elevated in the skin of vitiligo patients. Our aim was to examine nine known polymorphisms in the MYG1 gene, to investigate their functionality, and to study their association with vitiligo susceptibility.

U2 - 10.1186/1471-2350-11-56

DO - 10.1186/1471-2350-11-56

M3 - Journal article

C2 - 20377893

SN - 1471-2350

VL - 11

SP - 56

JO - B M C Medical Genetics

JF - B M C Medical Genetics

ER -

Promoter polymorphism -119C/G in MYG1 (C12orf10) gene is related to vitiligo susceptibility and Arg4Gln affects mitochondrial entrance of Myg1

Abstract

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