Proliferation of germ cells and somatic cells in first trimester human embryonic gonads as indicated by S and S+G2+M phase fractions

K P Sørensen, M C Lutterodt, L S Mamsen, A G Byskov, Jørgen Knud Larsen

    1 Citationer (Scopus)

    Abstract

    The number of germ cells and somatic cells in human embryonic and foetal gonads has previously been estimated by stereological methods, which are time- and labour-consuming with little information concerning cell proliferation. Here, we studied whether flow cytometry could be applied as an easier method, also enabling estimation of the fraction of cells in S or S+G(2)+M (SG(2) M) cell-cycle phases as indicators of cell proliferation.
    OriginalsprogEngelsk
    TidsskriftCell Proliferation
    Vol/bind44
    Udgave nummer3
    Sider (fra-til)224-33
    Antal sider10
    ISSN0960-7722
    DOI
    StatusUdgivet - 2011

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