Proinsulin, GLP-1, and glucagon are associated with partial remission in children and adolescents with newly diagnosed type 1 diabetes

Anne Kaas; Marie Louise Max Andersen; Siri Fredheim; Philip Hougaard; Karsten Buschard; Jacob Steen Petersen; Carine de Beaufort; Kenneth J Robertson; Lars Hansen; Henrik B Mortensen; Lotte B Nielsen; Hvidoere Study Group on childhood diabetes

doi:10.1111/j.1399-5448.2011.00812.x

Proinsulin, GLP-1, and glucagon are associated with partial remission in children and adolescents with newly diagnosed type 1 diabetes

Anne Kaas, Marie Louise Max Andersen, Siri Fredheim, Philip Hougaard, Karsten Buschard, Jacob Steen Petersen, Carine de Beaufort, Kenneth J Robertson, Lars Hansen, Henrik B Mortensen, Lotte B Nielsen, Hvidoere Study Group on childhood diabetes

19 Citationer (Scopus)

Abstract

Proinsulin is a marker of beta-cell distress and dysfunction in type 2 diabetes and transplanted islets. Proinsulin levels are elevated in patients newly diagnosed with type 1 diabetes. Our aim was to assess the relationship between proinsulin, insulin dose-adjusted haemoglobin A1c (IDAA1C), glucagon-like peptide-1 (GLP-1), glucagon, and remission status the first year after diagnosis of type 1 diabetes.

Originalsprog	Engelsk
Tidsskrift	Pediatric Diabetes
Vol/bind	13
Udgave nummer	1
Sider (fra-til)	51-8
Antal sider	8
ISSN	1399-543X
DOI	https://doi.org/10.1111/j.1399-5448.2011.00812.x
Status	Udgivet - 2012

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10.1111/j.1399-5448.2011.00812.x

Citationsformater

Kaas, A., Andersen, M. L. M., Fredheim, S., Hougaard, P., Buschard, K., Petersen, J. S., de Beaufort, C., Robertson, K. J., Hansen, L., Mortensen, H. B., Nielsen, L. B., & Hvidoere Study Group on childhood diabetes (2012). Proinsulin, GLP-1, and glucagon are associated with partial remission in children and adolescents with newly diagnosed type 1 diabetes. Pediatric Diabetes, 13(1), 51-8. https://doi.org/10.1111/j.1399-5448.2011.00812.x

Kaas, A, Andersen, MLM, Fredheim, S, Hougaard, P, Buschard, K, Petersen, JS, de Beaufort, C, Robertson, KJ, Hansen, L, Mortensen, HB, Nielsen, LB & Hvidoere Study Group on childhood diabetes 2012, 'Proinsulin, GLP-1, and glucagon are associated with partial remission in children and adolescents with newly diagnosed type 1 diabetes', Pediatric Diabetes, bind 13, nr. 1, s. 51-8. https://doi.org/10.1111/j.1399-5448.2011.00812.x

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title = "Proinsulin, GLP-1, and glucagon are associated with partial remission in children and adolescents with newly diagnosed type 1 diabetes",

abstract = "Proinsulin is a marker of beta-cell distress and dysfunction in type 2 diabetes and transplanted islets. Proinsulin levels are elevated in patients newly diagnosed with type 1 diabetes. Our aim was to assess the relationship between proinsulin, insulin dose-adjusted haemoglobin A1c (IDAA1C), glucagon-like peptide-1 (GLP-1), glucagon, and remission status the first year after diagnosis of type 1 diabetes.",

author = "Anne Kaas and Andersen, {Marie Louise Max} and Siri Fredheim and Philip Hougaard and Karsten Buschard and Petersen, {Jacob Steen} and {de Beaufort}, Carine and Robertson, {Kenneth J} and Lars Hansen and Mortensen, {Henrik B} and Nielsen, {Lotte B} and {Hvidoere Study Group on childhood diabetes}",

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year = "2012",

doi = "10.1111/j.1399-5448.2011.00812.x",

language = "English",

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T1 - Proinsulin, GLP-1, and glucagon are associated with partial remission in children and adolescents with newly diagnosed type 1 diabetes

AU - Kaas, Anne

AU - Andersen, Marie Louise Max

AU - Fredheim, Siri

AU - Hougaard, Philip

AU - Buschard, Karsten

AU - Petersen, Jacob Steen

AU - de Beaufort, Carine

AU - Robertson, Kenneth J

AU - Hansen, Lars

AU - Mortensen, Henrik B

AU - Nielsen, Lotte B

AU - Hvidoere Study Group on childhood diabetes

PY - 2012

Y1 - 2012

N2 - Proinsulin is a marker of beta-cell distress and dysfunction in type 2 diabetes and transplanted islets. Proinsulin levels are elevated in patients newly diagnosed with type 1 diabetes. Our aim was to assess the relationship between proinsulin, insulin dose-adjusted haemoglobin A1c (IDAA1C), glucagon-like peptide-1 (GLP-1), glucagon, and remission status the first year after diagnosis of type 1 diabetes.

AB - Proinsulin is a marker of beta-cell distress and dysfunction in type 2 diabetes and transplanted islets. Proinsulin levels are elevated in patients newly diagnosed with type 1 diabetes. Our aim was to assess the relationship between proinsulin, insulin dose-adjusted haemoglobin A1c (IDAA1C), glucagon-like peptide-1 (GLP-1), glucagon, and remission status the first year after diagnosis of type 1 diabetes.

U2 - 10.1111/j.1399-5448.2011.00812.x

DO - 10.1111/j.1399-5448.2011.00812.x

M3 - Journal article

C2 - 22118630

SN - 1399-543X

VL - 13

SP - 51

EP - 58

JO - Pediatric Diabetes

JF - Pediatric Diabetes

IS - 1

ER -

Proinsulin, GLP-1, and glucagon are associated with partial remission in children and adolescents with newly diagnosed type 1 diabetes

Abstract

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