Progression of subtle motor signs in PINK1 mutation carriers with mild dopaminergic deficit

C Eggers; A Schmidt; J Hagenah; N Brüggemann; J C Klein; V Tadic; L Kertelge; M Kasten; F Binkofski; H Siebner; B Neumaier; G R Fink; R Hilker; C Klein

doi:10.1212/WNL.0b013e3181e0f79c

Progression of subtle motor signs in PINK1 mutation carriers with mild dopaminergic deficit

C Eggers, A Schmidt, J Hagenah, N Brüggemann, J C Klein, V Tadic, L Kertelge, M Kasten, F Binkofski, H Siebner, B Neumaier, G R Fink, R Hilker, C Klein

Funktions- og Billeddiagnostisk Enhed, MR-Forskningssektionen

60 Citationer (Scopus)

Abstract

Udgivelsesdato: 2010-Jun-1

Originalsprog	Engelsk
Tidsskrift	Neurology
Vol/bind	74
Udgave nummer	22
Sider (fra-til)	1798-805
Antal sider	7
DOI	https://doi.org/10.1212/WNL.0b013e3181e0f79c
Status	Udgivet - 2010

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10.1212/WNL.0b013e3181e0f79c

Citationsformater

@article{b70069eb717742698accc4f5dc0ef802,

title = "Progression of subtle motor signs in PINK1 mutation carriers with mild dopaminergic deficit",

abstract = "While homozygous mutations in the PINK1 gene cause recessively inherited early-onset Parkinson disease (PD), heterozygous mutations have been suggested as a susceptibility factor.",

keywords = "Adult, Brain Mapping, Corpus Striatum, Dopamine, Female, Follow-Up Studies, Genetic Predisposition to Disease, Humans, Male, Middle Aged, Mutation, Parkinson Disease, Positron-Emission Tomography, Protein Kinases, Severity of Illness Index, Statistics, Nonparametric",

author = "C Eggers and A Schmidt and J Hagenah and N Br{\"u}ggemann and Klein, {J C} and V Tadic and L Kertelge and M Kasten and F Binkofski and H Siebner and B Neumaier and Fink, {G R} and R Hilker and C Klein",

year = "2010",

doi = "10.1212/WNL.0b013e3181e0f79c",

language = "English",

volume = "74",

pages = "1798--805",

journal = "Neurology",

issn = "1526-632X",

publisher = "Lippincott Williams and Wilkins",

number = "22",

}

TY - JOUR

T1 - Progression of subtle motor signs in PINK1 mutation carriers with mild dopaminergic deficit

AU - Eggers, C

AU - Schmidt, A

AU - Hagenah, J

AU - Brüggemann, N

AU - Klein, J C

AU - Tadic, V

AU - Kertelge, L

AU - Kasten, M

AU - Binkofski, F

AU - Siebner, H

AU - Neumaier, B

AU - Fink, G R

AU - Hilker, R

AU - Klein, C

PY - 2010

Y1 - 2010

N2 - While homozygous mutations in the PINK1 gene cause recessively inherited early-onset Parkinson disease (PD), heterozygous mutations have been suggested as a susceptibility factor.

AB - While homozygous mutations in the PINK1 gene cause recessively inherited early-onset Parkinson disease (PD), heterozygous mutations have been suggested as a susceptibility factor.

KW - Adult

KW - Brain Mapping

KW - Corpus Striatum

KW - Dopamine

KW - Female

KW - Follow-Up Studies

KW - Genetic Predisposition to Disease

KW - Humans

KW - Male

KW - Middle Aged

KW - Mutation

KW - Parkinson Disease

KW - Positron-Emission Tomography

KW - Protein Kinases

KW - Severity of Illness Index

KW - Statistics, Nonparametric

U2 - 10.1212/WNL.0b013e3181e0f79c

DO - 10.1212/WNL.0b013e3181e0f79c

M3 - Journal article

C2 - 20513816

SN - 1526-632X

VL - 74

SP - 1798

EP - 1805

JO - Neurology

JF - Neurology

IS - 22

ER -

Progression of subtle motor signs in PINK1 mutation carriers with mild dopaminergic deficit

Abstract

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