Progression of motor axon dysfunction and ectopic Nav1.8 expression in a mouse model of Charcot-Marie-Tooth disease 1B

Keyphrases

• Mouse Model 100%
• Motor Axon 100%
• Charcot-Marie-Tooth Disease 100%
• Nav1.8 100%
• Tibial Nerve 50%
• Progressive Reduction 50%
• Demyelinating Neuropathy 50%
• CMT1B 50%
• Latency 25%
• Histology 25%
• Functional Impairment 25%
• Excitability 25%
• Ankle 25%
• Myelin Basic Protein 25%
• Axon Excitability 25%
• Conduction Failure 25%
• Demyelinating 25%
• Threshold Tracking 25%
• Pharmacologic 25%
• Neuropathy 25%
• Plantar 25%
• Littermate 25%
• Mathematical Modeling 25%
• Long-term Development 25%
• Motor Performance 25%
• Threshold Electrotonus 25%
• Strength-duration Time Constant 25%
• Motor Dysfunction 25%
• Compound muscle Action Potential 25%
• Tracking Studies 25%
• Reduced Compounds 25%
• Resting Membrane Potential 25%
• Na Current 25%
• V-slope 25%
• Compound muscle Action Potential Amplitude 25%
• Cable Properties 25%

Medicine and Dentistry

• Axon 100%
• DeJerine-Sottas Disease 100%
• Nav1.8 100%
• Tibial Nerve 50%
• Compound Muscle Action Potential 50%
• Demyelinating Neuropathy 50%
• Excitability 25%
• Functional Disease 25%
• Myelin Protein 25%
• Motor Performance 25%
• Neuropathy 25%
• Stereotypic Movement Disorder 25%
• Nerve Excitability 25%
• Action Potential Amplitude 25%
• Membrane Steady Potential 25%

Neuroscience

• Peripheral Neuropathy 100%
• Axon 100%
• Charcot-Marie-Tooth Disease 100%
• Tibial Nerve 66%
• Excitability 33%
• Action Potential 33%
• Evoked Potential 33%
• Myelin Protein 33%
• Nerve Excitability 33%
• Stereotypic Movement Disorder 33%
• Resting Potential 33%