Prognostic value of Bcl-2 in two independent populations of estrogen receptor positive breast cancer patients treated with adjuvant endocrine therapy

Mathilde S Larsen, Karsten Bjerre, Anita Giobbie-Hurder, Anne-Vibeke Lænkholm, Katrine L Henriksen, Bent Ejlertsen, Anne Elisabeth Lykkesfeldt, Birgitte B Rasmussen

18 Citationer (Scopus)

Abstract

Estrogen receptor (ER) status is not an optimal marker for response to adjuvant endocrine therapy since approximately 30% of patients with ER-positive tumors eventually relapse. Bcl-2 is regulated by ER and may thus be considered as an indicator of ER activity and a candidate supplementary marker to ER status.
OriginalsprogEngelsk
TidsskriftActa Oncologica
Vol/bind51
Udgave nummer6
Sider (fra-til)781-9
Antal sider9
ISSN0284-186X
DOI
StatusUdgivet - 2012

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