Prognostic significance of interleukin-7 receptor-α gene polymorphisms in allogeneic stem-cell transplantation: a confirmatory study

Zaiba Shamim; Lars P Ryder; Ib J Christensen; Antoine Toubert; Jean Norden; Matthew Collin; Graham Jackson; Anne M Dickinson; Klaus Müller

doi:10.1097/TP.0b013e31820f08b2

Prognostic significance of interleukin-7 receptor-α gene polymorphisms in allogeneic stem-cell transplantation: a confirmatory study

Zaiba Shamim, Lars P Ryder, Ib J Christensen, Antoine Toubert, Jean Norden, Matthew Collin, Graham Jackson, Anne M Dickinson, Klaus Müller

19 Citationer (Scopus)

Abstract

Interleukin-7 (IL-7) is a hematopoietic cytokine essential for T-cell development in the thymus and for the maintenance of peripheral T cells. A previous study of single nucleotide polymorphisms in the exons of IL-7 receptor α-chain (IL-7Rα) in a Danish cohort of patients undergoing allogeneic stem-cell transplantation (SCT) identified donor genotype GG at rs1494555 as a risk factor for treatment-related mortality (TRM) after SCT.

Originalsprog	Engelsk
Tidsskrift	Transplantation
Vol/bind	91
Udgave nummer	7
Sider (fra-til)	731-6
Antal sider	6
ISSN	0041-1337
DOI	https://doi.org/10.1097/TP.0b013e31820f08b2
Status	Udgivet - 15 apr. 2011

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10.1097/TP.0b013e31820f08b2

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title = "Prognostic significance of interleukin-7 receptor-α gene polymorphisms in allogeneic stem-cell transplantation: a confirmatory study",

abstract = "Interleukin-7 (IL-7) is a hematopoietic cytokine essential for T-cell development in the thymus and for the maintenance of peripheral T cells. A previous study of single nucleotide polymorphisms in the exons of IL-7 receptor α-chain (IL-7Rα) in a Danish cohort of patients undergoing allogeneic stem-cell transplantation (SCT) identified donor genotype GG at rs1494555 as a risk factor for treatment-related mortality (TRM) after SCT.",

author = "Zaiba Shamim and Ryder, {Lars P} and Christensen, {Ib J} and Antoine Toubert and Jean Norden and Matthew Collin and Graham Jackson and Dickinson, {Anne M} and Klaus M{\"u}ller",

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T1 - Prognostic significance of interleukin-7 receptor-α gene polymorphisms in allogeneic stem-cell transplantation: a confirmatory study

AU - Shamim, Zaiba

AU - Ryder, Lars P

AU - Christensen, Ib J

AU - Toubert, Antoine

AU - Norden, Jean

AU - Collin, Matthew

AU - Jackson, Graham

AU - Dickinson, Anne M

AU - Müller, Klaus

PY - 2011/4/15

Y1 - 2011/4/15

N2 - Interleukin-7 (IL-7) is a hematopoietic cytokine essential for T-cell development in the thymus and for the maintenance of peripheral T cells. A previous study of single nucleotide polymorphisms in the exons of IL-7 receptor α-chain (IL-7Rα) in a Danish cohort of patients undergoing allogeneic stem-cell transplantation (SCT) identified donor genotype GG at rs1494555 as a risk factor for treatment-related mortality (TRM) after SCT.

AB - Interleukin-7 (IL-7) is a hematopoietic cytokine essential for T-cell development in the thymus and for the maintenance of peripheral T cells. A previous study of single nucleotide polymorphisms in the exons of IL-7 receptor α-chain (IL-7Rα) in a Danish cohort of patients undergoing allogeneic stem-cell transplantation (SCT) identified donor genotype GG at rs1494555 as a risk factor for treatment-related mortality (TRM) after SCT.

U2 - 10.1097/TP.0b013e31820f08b2

DO - 10.1097/TP.0b013e31820f08b2

M3 - Journal article

C2 - 21326139

SN - 0041-1337

VL - 91

SP - 731

EP - 736

JO - Transplantation

JF - Transplantation

IS - 7

ER -

Prognostic significance of interleukin-7 receptor-α gene polymorphisms in allogeneic stem-cell transplantation: a confirmatory study

Abstract

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