Proghrelin peptides: Desacyl ghrelin is a powerful inhibitor of acylated ghrelin, likely to impair physiological effects of acyl ghrelin but not of obestatin A study of pancreatic polypeptide secretion from mouse islets

Rajesh Kumar; Albert Salehi; Jens F Rehfeld; Peter Höglund; Erik Lindström; Rolf Håkanson

doi:10.1016/j.regpep.2010.06.005

Proghrelin peptides: Desacyl ghrelin is a powerful inhibitor of acylated ghrelin, likely to impair physiological effects of acyl ghrelin but not of obestatin A study of pancreatic polypeptide secretion from mouse islets

Rajesh Kumar, Albert Salehi, Jens F Rehfeld, Peter Höglund, Erik Lindström, Rolf Håkanson

Afdeling for Klinisk Biokemi

38 Citationer (Scopus)

Abstract

Proghrelin, produced by the ghrelin (A-like) cells of the gastric mucosa, gives rise to cleavage products, including desacyl ghrelin, acyl ghrelin and obestatin. The products are thought to be secreted concomitantly. In an earlier study we found acyl ghrelin and obestatin, but not desacyl ghrelin, to suppress the release of hormones from isolated islets of mouse and rat pancreas.

Originalsprog	Engelsk
Tidsskrift	Regulatory Peptides
Vol/bind	164
Udgave nummer	2-3
Sider (fra-til)	65-70
Antal sider	6
ISSN	0167-0115
DOI	https://doi.org/10.1016/j.regpep.2010.06.005
Status	Udgivet - 24 sep. 2010

Adgang til dokumentet

10.1016/j.regpep.2010.06.005

Fingeraftryk

Dyk ned i forskningsemnerne om 'Proghrelin peptides: Desacyl ghrelin is a powerful inhibitor of acylated ghrelin, likely to impair physiological effects of acyl ghrelin but not of obestatin A study of pancreatic polypeptide secretion from mouse islets'. Sammen danner de et unikt fingeraftryk.

Citationsformater

Kumar, R., Salehi, A., Rehfeld, J. F., Höglund, P., Lindström, E., & Håkanson, R. (2010). Proghrelin peptides: Desacyl ghrelin is a powerful inhibitor of acylated ghrelin, likely to impair physiological effects of acyl ghrelin but not of obestatin A study of pancreatic polypeptide secretion from mouse islets. Regulatory Peptides, 164(2-3), 65-70. https://doi.org/10.1016/j.regpep.2010.06.005

Proghrelin peptides: Desacyl ghrelin is a powerful inhibitor of acylated ghrelin, likely to impair physiological effects of acyl ghrelin but not of obestatin A study of pancreatic polypeptide secretion from mouse islets. / Kumar, Rajesh; Salehi, Albert; Rehfeld, Jens F et al.
I: Regulatory Peptides, Bind 164, Nr. 2-3, 24.09.2010, s. 65-70.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Kumar, R, Salehi, A, Rehfeld, JF, Höglund, P, Lindström, E & Håkanson, R 2010, 'Proghrelin peptides: Desacyl ghrelin is a powerful inhibitor of acylated ghrelin, likely to impair physiological effects of acyl ghrelin but not of obestatin A study of pancreatic polypeptide secretion from mouse islets', Regulatory Peptides, bind 164, nr. 2-3, s. 65-70. https://doi.org/10.1016/j.regpep.2010.06.005

Kumar R, Salehi A, Rehfeld JF, Höglund P, Lindström E, Håkanson R. Proghrelin peptides: Desacyl ghrelin is a powerful inhibitor of acylated ghrelin, likely to impair physiological effects of acyl ghrelin but not of obestatin A study of pancreatic polypeptide secretion from mouse islets. Regulatory Peptides. 2010 sep. 24;164(2-3):65-70. doi: 10.1016/j.regpep.2010.06.005

@article{7a63364c3c164d2eb2a0816a5d6fd454,

title = "Proghrelin peptides: Desacyl ghrelin is a powerful inhibitor of acylated ghrelin, likely to impair physiological effects of acyl ghrelin but not of obestatin A study of pancreatic polypeptide secretion from mouse islets",

abstract = "Proghrelin, produced by the ghrelin (A-like) cells of the gastric mucosa, gives rise to cleavage products, including desacyl ghrelin, acyl ghrelin and obestatin. The products are thought to be secreted concomitantly. In an earlier study we found acyl ghrelin and obestatin, but not desacyl ghrelin, to suppress the release of hormones from isolated islets of mouse and rat pancreas.",

author = "Rajesh Kumar and Albert Salehi and Rehfeld, {Jens F} and Peter H{\"o}glund and Erik Lindstr{\"o}m and Rolf H{\aa}kanson",

year = "2010",

month = sep,

day = "24",

doi = "10.1016/j.regpep.2010.06.005",

language = "English",

volume = "164",

pages = "65--70",

journal = "Regulatory Peptides",

issn = "0167-0115",

publisher = "Elsevier",

number = "2-3",

}

TY - JOUR

T1 - Proghrelin peptides: Desacyl ghrelin is a powerful inhibitor of acylated ghrelin, likely to impair physiological effects of acyl ghrelin but not of obestatin A study of pancreatic polypeptide secretion from mouse islets

AU - Kumar, Rajesh

AU - Salehi, Albert

AU - Rehfeld, Jens F

AU - Höglund, Peter

AU - Lindström, Erik

AU - Håkanson, Rolf

PY - 2010/9/24

Y1 - 2010/9/24

N2 - Proghrelin, produced by the ghrelin (A-like) cells of the gastric mucosa, gives rise to cleavage products, including desacyl ghrelin, acyl ghrelin and obestatin. The products are thought to be secreted concomitantly. In an earlier study we found acyl ghrelin and obestatin, but not desacyl ghrelin, to suppress the release of hormones from isolated islets of mouse and rat pancreas.

AB - Proghrelin, produced by the ghrelin (A-like) cells of the gastric mucosa, gives rise to cleavage products, including desacyl ghrelin, acyl ghrelin and obestatin. The products are thought to be secreted concomitantly. In an earlier study we found acyl ghrelin and obestatin, but not desacyl ghrelin, to suppress the release of hormones from isolated islets of mouse and rat pancreas.

U2 - 10.1016/j.regpep.2010.06.005

DO - 10.1016/j.regpep.2010.06.005

M3 - Journal article

C2 - 20619300

SN - 0167-0115

VL - 164

SP - 65

EP - 70

JO - Regulatory Peptides

JF - Regulatory Peptides

IS - 2-3

ER -