TY - JOUR
T1 - Profiling abdominal aortic aneurysm growth with three-dimensional ultrasound
AU - Broda, Magdalena
AU - Rouet, Laurence
AU - Zielinski, Alexander
AU - Sillesen, Henrik
AU - Eiberg, Jonas
AU - Ghulam, Qasam
PY - 2022/2
Y1 - 2022/2
N2 - BACKGROUND: Profiling is a new method based on three-dimensional ultrasound (3D-US) allowing for direct comparison of baseline and follow-up diameters along the AAA length. This study aimed to evaluate the feasibility of profiling to visualize AAA changes at submaximum diameters, and to categorize the growth profiles.METHODS: This is a retrospective analysis of prospectively and consecutively included patients under AAA surveillance at a tertiary referral center. 3D-US images of AAAs at baseline and at one-year follow-up were segmented, generating a centerline and a mesh of the aneurysm geometry. The mesh was processed to illustrate diameter changes of a given AAA. Three growth profiles were identified: 1) peak growth (the largest, significant [≥3.6 mm] diameter difference occurred within a 10 mm margin to either side of the maximum baseline diameter); B) edge growth (at least one significant diameter difference and the criteria for peak growth did not apply); and 3) no growth (all diameter differences were nonsignificant). A centerline length of ≥60 mm was assumed to capture a comparable segment of the wall geometry at baseline and follow-up. Cohen's kappa and Kaplan Meier analysis were used to analyze data.RESULTS: In total, 186 patients had growth profiles generated. Of these, 28 (15%) were discarded, mainly based on inadequate centerline lengths (N.=21, 11.3%). The remaining patients were categorized into edge growth (N.=83, 52%), no growth (N.=47, 30%), and peak growth (N.=28, 18%).CONCLUSIONS: Profiling interprets AAA growth at submaximum diameters. Half of the cohort had edge growth. These AAAs risk being classified as stable.
AB - BACKGROUND: Profiling is a new method based on three-dimensional ultrasound (3D-US) allowing for direct comparison of baseline and follow-up diameters along the AAA length. This study aimed to evaluate the feasibility of profiling to visualize AAA changes at submaximum diameters, and to categorize the growth profiles.METHODS: This is a retrospective analysis of prospectively and consecutively included patients under AAA surveillance at a tertiary referral center. 3D-US images of AAAs at baseline and at one-year follow-up were segmented, generating a centerline and a mesh of the aneurysm geometry. The mesh was processed to illustrate diameter changes of a given AAA. Three growth profiles were identified: 1) peak growth (the largest, significant [≥3.6 mm] diameter difference occurred within a 10 mm margin to either side of the maximum baseline diameter); B) edge growth (at least one significant diameter difference and the criteria for peak growth did not apply); and 3) no growth (all diameter differences were nonsignificant). A centerline length of ≥60 mm was assumed to capture a comparable segment of the wall geometry at baseline and follow-up. Cohen's kappa and Kaplan Meier analysis were used to analyze data.RESULTS: In total, 186 patients had growth profiles generated. Of these, 28 (15%) were discarded, mainly based on inadequate centerline lengths (N.=21, 11.3%). The remaining patients were categorized into edge growth (N.=83, 52%), no growth (N.=47, 30%), and peak growth (N.=28, 18%).CONCLUSIONS: Profiling interprets AAA growth at submaximum diameters. Half of the cohort had edge growth. These AAAs risk being classified as stable.
KW - Aortic Aneurysm, Abdominal/diagnostic imaging
KW - Humans
KW - Imaging, Three-Dimensional/methods
KW - Kaplan-Meier Estimate
KW - Retrospective Studies
KW - Ultrasonography/methods
UR - http://www.scopus.com/inward/record.url?scp=85125011492&partnerID=8YFLogxK
U2 - 10.23736/S0392-9590.21.04724-6
DO - 10.23736/S0392-9590.21.04724-6
M3 - Journal article
C2 - 34672485
SN - 0392-9590
VL - 41
SP - 33
EP - 40
JO - International angiology : a journal of the International Union of Angiology
JF - International angiology : a journal of the International Union of Angiology
IS - 1
ER -