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Primary diagnosis of multiple pheochromocytomas in the brother of a MEN-2 patient by simultaneous MIBG scintigraphy and low-dose computed tomography

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@article{276ece72914d4d7b9ffd94092e5c0c79,
title = "Primary diagnosis of multiple pheochromocytomas in the brother of a MEN-2 patient by simultaneous MIBG scintigraphy and low-dose computed tomography",
abstract = "Metaiodobenzylguanidine (MIBG) scintigraphy is a well-established functional imaging method for localizing pheochromocytomas. However, the morphologic information revealed on the scintigram is often too sparse and thus, accordingly, supplemental computed tomography (CT) or magnetic resonance imaging are often performed. Recently, gamma cameras with built-in low-dose CT were introduced. The authors describe a patient with a high likelihood of pheochromocytoma who had simultaneous MIBG scintigraphy and low-dose CT performed as the primary examinations. The scan revealed pheochromocytomas in both adrenal glands and one extra-adrenal pheochromocytoma located in the liver. The combined imaging ensured the final diagnosis without any need for further imaging. Based on the findings of this case, the authors believe that combined MIBG scintigraphy and low-dose CT is a promising future single imaging technique for pheochromocytomas.",
keywords = "3-Iodobenzylguanidine, Adrenal Gland Neoplasms/diagnostic imaging, Aged, Female, Genetic Predisposition to Disease, Genetic Testing, Humans, Liver Neoplasms/diagnostic imaging, Male, Multiple Endocrine Neoplasia Type 2a/diagnosis, Pheochromocytoma/diagnostic imaging, Radionuclide Imaging/methods, Siblings, Tomography, X-Ray Computed/methods",
author = "Andreas Kjaer and Petersen, {Claus Leth}",
year = "2002",
month = "12",
language = "English",
volume = "27",
pages = "868--70",
journal = "Clinical Nuclear Medicine",
issn = "0363-9762",
publisher = "Lippincott Williams & Wilkins",
number = "12",

}

RIS

TY - JOUR

T1 - Primary diagnosis of multiple pheochromocytomas in the brother of a MEN-2 patient by simultaneous MIBG scintigraphy and low-dose computed tomography

AU - Kjaer, Andreas

AU - Petersen, Claus Leth

PY - 2002/12

Y1 - 2002/12

N2 - Metaiodobenzylguanidine (MIBG) scintigraphy is a well-established functional imaging method for localizing pheochromocytomas. However, the morphologic information revealed on the scintigram is often too sparse and thus, accordingly, supplemental computed tomography (CT) or magnetic resonance imaging are often performed. Recently, gamma cameras with built-in low-dose CT were introduced. The authors describe a patient with a high likelihood of pheochromocytoma who had simultaneous MIBG scintigraphy and low-dose CT performed as the primary examinations. The scan revealed pheochromocytomas in both adrenal glands and one extra-adrenal pheochromocytoma located in the liver. The combined imaging ensured the final diagnosis without any need for further imaging. Based on the findings of this case, the authors believe that combined MIBG scintigraphy and low-dose CT is a promising future single imaging technique for pheochromocytomas.

AB - Metaiodobenzylguanidine (MIBG) scintigraphy is a well-established functional imaging method for localizing pheochromocytomas. However, the morphologic information revealed on the scintigram is often too sparse and thus, accordingly, supplemental computed tomography (CT) or magnetic resonance imaging are often performed. Recently, gamma cameras with built-in low-dose CT were introduced. The authors describe a patient with a high likelihood of pheochromocytoma who had simultaneous MIBG scintigraphy and low-dose CT performed as the primary examinations. The scan revealed pheochromocytomas in both adrenal glands and one extra-adrenal pheochromocytoma located in the liver. The combined imaging ensured the final diagnosis without any need for further imaging. Based on the findings of this case, the authors believe that combined MIBG scintigraphy and low-dose CT is a promising future single imaging technique for pheochromocytomas.

KW - 3-Iodobenzylguanidine

KW - Adrenal Gland Neoplasms/diagnostic imaging

KW - Aged

KW - Female

KW - Genetic Predisposition to Disease

KW - Genetic Testing

KW - Humans

KW - Liver Neoplasms/diagnostic imaging

KW - Male

KW - Multiple Endocrine Neoplasia Type 2a/diagnosis

KW - Pheochromocytoma/diagnostic imaging

KW - Radionuclide Imaging/methods

KW - Siblings

KW - Tomography, X-Ray Computed/methods

M3 - Journal article

VL - 27

SP - 868

EP - 870

JO - Clinical Nuclear Medicine

JF - Clinical Nuclear Medicine

SN - 0363-9762

IS - 12

ER -

ID: 55074914