Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial--Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial

Peter S Sever; Björn Dahlöf; Neil R Poulter; Hans Wedel; Gareth Beevers; Mark Caulfield; Rory Collins; Sverre E Kjeldsen; Arni Kristinsson; Gordon T McInnes; Jesper Mehlsen; Markku Nieminen; Eoin O'Brien; Jan Ostergren; ASCOT Investigators

doi:10.1016/S0140-6736(03)12948-0

Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial--Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial

Peter S Sever, Björn Dahlöf, Neil R Poulter, Hans Wedel, Gareth Beevers, Mark Caulfield, Rory Collins, Sverre E Kjeldsen, Arni Kristinsson, Gordon T McInnes, Jesper Mehlsen, Markku Nieminen, Eoin O'Brien, Jan Ostergren, ASCOT Investigators

Klinisk Fysiologisk/Nuklearmedicinsk Afd.

3512 Citationer (Scopus)

Abstract

The lowering of cholesterol concentrations in individuals at high risk of cardiovascular disease improves outcome. No study, however, has assessed benefits of cholesterol lowering in the primary prevention of coronary heart disease (CHD) in hypertensive patients who are not conventionally deemed dyslipidaemic.

Originalsprog	Engelsk
Tidsskrift	Lancet
Vol/bind	361
Udgave nummer	9364
Sider (fra-til)	1149-58
Antal sider	10
ISSN	0140-6736
DOI	https://doi.org/10.1016/S0140-6736(03)12948-0
Status	Udgivet - 5 apr. 2003

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10.1016/S0140-6736(03)12948-0

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Citationsformater

Sever, P. S., Dahlöf, B., Poulter, N. R., Wedel, H., Beevers, G., Caulfield, M., Collins, R., Kjeldsen, S. E., Kristinsson, A., McInnes, G. T., Mehlsen, J., Nieminen, M., O'Brien, E., Ostergren, J., & ASCOT Investigators (2003). Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial--Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial. Lancet, 361(9364), 1149-58. https://doi.org/10.1016/S0140-6736(03)12948-0

Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial--Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial. / Sever, Peter S; Dahlöf, Björn; Poulter, Neil R et al.
I: Lancet, Bind 361, Nr. 9364, 05.04.2003, s. 1149-58.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Sever, PS, Dahlöf, B, Poulter, NR, Wedel, H, Beevers, G, Caulfield, M, Collins, R, Kjeldsen, SE, Kristinsson, A, McInnes, GT, Mehlsen, J, Nieminen, M, O'Brien, E, Ostergren, J & ASCOT Investigators 2003, 'Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial--Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial', Lancet, bind 361, nr. 9364, s. 1149-58. https://doi.org/10.1016/S0140-6736(03)12948-0

Sever PS, Dahlöf B, Poulter NR, Wedel H, Beevers G, Caulfield M et al. Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial--Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial. Lancet. 2003 apr. 5;361(9364):1149-58. doi: 10.1016/S0140-6736(03)12948-0

Sever, Peter S ; Dahlöf, Björn ; Poulter, Neil R et al. / Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial--Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial. I: Lancet. 2003 ; Bind 361, Nr. 9364. s. 1149-58.

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abstract = "The lowering of cholesterol concentrations in individuals at high risk of cardiovascular disease improves outcome. No study, however, has assessed benefits of cholesterol lowering in the primary prevention of coronary heart disease (CHD) in hypertensive patients who are not conventionally deemed dyslipidaemic.",

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AU - Dahlöf, Björn

AU - Poulter, Neil R

AU - Wedel, Hans

AU - Beevers, Gareth

AU - Caulfield, Mark

AU - Collins, Rory

AU - Kjeldsen, Sverre E

AU - Kristinsson, Arni

AU - McInnes, Gordon T

AU - Mehlsen, Jesper

AU - Nieminen, Markku

AU - O'Brien, Eoin

AU - Ostergren, Jan

AU - ASCOT Investigators

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N2 - The lowering of cholesterol concentrations in individuals at high risk of cardiovascular disease improves outcome. No study, however, has assessed benefits of cholesterol lowering in the primary prevention of coronary heart disease (CHD) in hypertensive patients who are not conventionally deemed dyslipidaemic.

AB - The lowering of cholesterol concentrations in individuals at high risk of cardiovascular disease improves outcome. No study, however, has assessed benefits of cholesterol lowering in the primary prevention of coronary heart disease (CHD) in hypertensive patients who are not conventionally deemed dyslipidaemic.

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DO - 10.1016/S0140-6736(03)12948-0

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SN - 0140-6736

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