Prevalence of hyperglycaemia and undiagnosed diabetes mellitus in patients with acute myocardial infarction

J K Madsen, S Haunsøe, S Helquist, E Hommel, I Malthe, N T Pedersen, H Sengeløv, D Rønnow-Jessen, S Telmer, H H Parving

34 Citationer (Scopus)

Abstract

The prevalence of hyperglycaemia and undiagnosed diabetes mellitus was assessed in 214 consecutive patients admitted to the coronary care units with acute myocardial infarction (AMI). On admission, 16 patients (7.5%) had known diabetes, and 19 patients, not previously known to be diabetic, had blood glucose concentrations of greater than or equal to 9 mmol/l. Fifteen patients survived for 2 months at which time a 75 g oral glucose tolerance test showed diabetes in 9 (60%) and impaired glucose tolerance in 4 (27%). Ten of these 13 patients (77%) with abnormal glucose tolerance had elevated glycosylated haemoglobin (HbA1c) on admission, indicating pre-existing glucose intolerance or diabetes. The prevalence of undiagnosed diabetes was 4.5% (9/198). However, we may have overlooked undiagnosed diabetes in a small number of patients on admission, since only a random blood glucose less than 8 mmol/l rules out diabetes, WHO criteria. Elevated blood glucose in patients with AMI is more likely to reflect a stationary pre-existing abnormal glucose tolerance than a temporary stress-induced phenomenon.

OriginalsprogEngelsk
TidsskriftActa Medica Scandinavica
Vol/bind220
Udgave nummer4
Sider (fra-til)329-32
Antal sider4
ISSN0001-6101
DOI
StatusUdgivet - 1986
Udgivet eksterntJa

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