Prevalence of hiv infection in seronegative high-risk individuals examined by virus isolation and pcr

Claus Nielsen*, Lars Stubbe Teglbjaerg, Court Pedersen, Jens Dilling Lundgren, Carsten Møller Nielsen, Bent Faber Vestergaard

*Corresponding author af dette arbejde
8 Citationer (Scopus)

Abstract

HIV seronegative individuals with high-risk behavior were tested for HIV infection by sensitive virus isolation techniques using T4 lymphocytes and monocyte/macrophages, and by detection of proviral DNA using PCR with three different sets of nested primers. No evidence of HIV infection was found among the 31 seronegative high-risk subjects, either by virus isolation of by PCR (97.5% confidence limits, 0-11). Our results indicate that ongoing HIV infection in seronegative persons at high risk of infection is a rare event.

OriginalsprogEngelsk
TidsskriftJournal of Acquired Immune Deficiency Syndromes
Vol/bind4
Udgave nummer11
Sider (fra-til)1107-1111
Antal sider5
ISSN1525-4135
StatusUdgivet - nov. 1991
Udgivet eksterntJa

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