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Region Hovedstaden - en del af Københavns Universitetshospital
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Prevalence of family history in patients with reflex syncope

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

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Reflex syncope is defined by a rapid transient loss of consciousness caused by global cerebral hypoperfusion resulting from vasodilatation and/or bradycardia attributable to inappropriate cardiovascular reflexes. A hereditary component has been suggested, but prevalence of family history may differ among subtypes of reflex syncope, as these have different autonomic responses and pathogeneses may be diverse. The present study aimed to assess the prevalence of a positive family history of syncope and cardiovascular characteristics in patients with cardioinhibitory and vasodepressor reflex syncope. Patients (n=74) were classified into subtypes of reflex syncope - cardioinhibition/asystole (Vasovagal Syncope International Study subtypes II-B [VASIS II-B], n=38) or vasodepressor (VASIS III, n=36) - using the head-up tilt test. Family history was obtained by questionnaires supplemented by interview. Patients with cardioinhibitory syncope had a mean onset of disease 8 years earlier than vasodepressor patients (mean ± standard deviation 14.5 years ± 12.6 for cardioinhibitory patients compared to 22.4 years ± 11.9 for vasodepressor patients, p
OriginalsprogEngelsk
TidsskriftJournal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Vol/bind20
Udgave nummer5
Sider (fra-til)692-6
Antal sider5
DOI
StatusUdgivet - maj 2013

ID: 42202260