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Region Hovedstaden - en del af Københavns Universitetshospital
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Prevalence and socio-demographic characteristics of persons who have never had a headache among healthy voluntary blood donors – a population-based study

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Introduction: Headache is an extremely prevalent disorder with a lifetime prevalence of 90–99%. However, a small fraction of people never experiences a headache. Research on people without headache could uncover protective factors in headache, but to our knowledge no study on headache-free individuals has been published. We aim to estimate the prevalence of headache-free individuals among Danish blood donors, and to describe the socio-demographics and health factors of headache-free participants. Materials and methods: In all, 38,557 healthy volunteers were recruited as part of the Danish Blood Donor Study. Headache-free participants were identified based on the question “Have you ever experienced a headache of any kind?”. Utilising the Danish registries and self-reported questionnaires, we analysed socio-demographic and lifestyle factors using logistic regression adjusted for age and sex. Results: The prevalence of headache-free individuals was 4.1% (n = 1362) with a female-male ratio of 1:2.2. To be headache free was significantly associated with an employment status as a student, a low level of income and a regular alcohol consumption. Discussion: The prevalence of headache-free individuals was comparable to population-wide studies of headache. To be headache free was not associated with a high socio-economic status. Further studies on people without headache will hopefully reveal protective factors in headache, and this novel approach might be useful in other very prevalent disorders.

OriginalsprogEngelsk
TidsskriftCephalalgia
Vol/bind40
Udgave nummer10
Sider (fra-til)1055-1062
ISSN0333-1024
DOI
StatusUdgivet - 2020

Bibliografisk note

Funding Information:
We wish to express a special thanks to the staff of the Danish blood banks, whose continued inclusion of blood donors into the DBDS makes this research possible.

ID: 59829690