Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
E-pub ahead of print

Prevalence and risk of occult cancer in stroke

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Circulating nociceptin and CGRP in medication-overuse headache

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Neurostimulation for the treatment of chronic migraine and cluster headache

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  3. Personality traits in migraine and medication-overuse headache: A comparative study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Treatment of spatial neglect in clinical practice: A nationwide survey

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Optical coherence tomography in acute optic neuritis: A population-based study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Social Inequality by Income in Short- and Long-Term Cause-Specific Mortality after Stroke

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Married, unmarried, divorced, and widowed and the risk of stroke

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Risk of Ischemic and Hemorrhagic Strokes in Occult and Manifest Cancers

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Risk of Stroke in Migraineurs Using Triptans. Associations with Age, Sex, Stroke Severity and Subtype

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Sex Disparities in Stroke: Women Have More Severe Strokes but Better Survival Than Men

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

OBJECTIVES: Cancer is associated with higher risk of stroke. Whether this translates into higher risk of cancer in stroke of an extent calling for cancer screening in stroke is unclear. We investigated prevalence and risk of occult cancer in stroke compared to the background population without history of stroke.

MATERIALS AND METHODS: All patients >40 years of age with incident stroke in Denmark 2003-2015 were identified through the Danish Stroke Registry (n = 85 893) and matched 1:10 on age and sex to the Danish background population without history of stroke (n = 858 740). Linking data to the Danish Cancer Registry, we determined prevalence of occult cancer in stroke defined as the event of previously unknown cancer during a 1-year follow-up in the stroke and in the background population. Cox regression models were used to study risk in comparison to the background population.

RESULTS: Prevalence (per 1000) of occult cancer in the stroke/background cohorts was 25.0/15.8 in women and 29.8/20.4 in men. Prevalence was dependent on age and sex. Highest among stroke patients aged 70-80 years (35.6 in women, 42.4 in men); lowest in patients aged 40-50 years (8.3 in women, 6.8 in men). Stroke was associated with an overall 54% higher risk of occult cancer but risk increased significantly with smoking, hazard ratio (HR) 1.47, age HR 1.27 per 10 years, male sex HR 1.25, and diabetes HR 1.25.

CONCLUSIONS: Prevalence and risk of occult cancer in stroke is considerable and calls for attention when designing the stroke investigation program.

OriginalsprogEngelsk
TidsskriftActa Neurologica Scandinavica
ISSN0001-6314
DOI
StatusE-pub ahead of print - 7 nov. 2019

Bibliografisk note

© 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

ID: 58573813