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Region Hovedstaden - en del af Københavns Universitetshospital
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Prevalence and predictors of irritable bowel syndrome in patients with morbid obesity: a cross-sectional study

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  • Martin Aasbrenn
  • Ingvild Høgestøl
  • Inger Eribe
  • Jon Kristinsson
  • Stian Lydersen
  • Tom Mala
  • Per G Farup
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BACKGROUND: Irritable bowel syndrome has been reported as more common in patients with morbid obesity than in the general population. The reason for this association is unknown. The aims of this study were to study the prevalence of irritable bowel syndrome and other functional bowel disorders in patients with morbid obesity, and to search for predictors of irritable bowel syndrome.

METHODS: Patients opting for bariatric surgery at two obesity centers in South-Eastern Norway were included. Functional bowel disorders were diagnosed according to the Rome III criteria. Predictors were evaluated in a multivariable logistic regression analysis with irritable bowel syndrome as the dependent variable.

RESULTS: A total of 350 (58%) out of 603 consecutive patients were included. The prevalence rates of irritable bowel syndrome at the two centers were 17/211 (8%) and 37/139 (27%) respectively. High low-density lipoprotein (OR 2.10; 95% CI 1.34-3.29), self-reported psychiatric disorders (OR 2.39; 95% CI 1.12-5.08) and center (OR 5.22; 95% CI 2.48-10.99) were independent predictors of irritable bowel syndrome.

CONCLUSIONS: At one of the two obesity centers, the prevalence of irritable bowel syndrome was threefold higher than in the general population in the same region. The high prevalence appears to be related to dietary differences or altered absorption or metabolism of fat. Attention to irritable bowel syndrome is important in the care of patients with morbid obesity.

OriginalsprogEngelsk
TidsskriftBMC Obesity
Vol/bind4
Sider (fra-til)22
ISSN2052-9538
DOI
StatusUdgivet - 2018
Eksternt udgivetJa

ID: 56705594