Presumed pluripotency markers UTF-1 and REX-1 are expressed in human adult testes and germ cell neoplasms

David M Kristensen, John E Nielsen, Niels E Skakkebaek, Niels Graem, Grete K Jacobsen, Ewa Rajpert-De Meyts, Henrik Leffers

82 Citationer (Scopus)

Abstract

UTF-1 and REX-1/ZFP42 are transcription factors involved in pluripotency. Because of phenotypic similarities between pluripotent embryonic stem cells and testicular germ cell tumours (TGCT) and the derivation of pluripotent cells from testes, we investigated the expression of UTF-1 and REX-1 during human gonadal development and in TGCT.
OriginalsprogEngelsk
TidsskriftHuman reproduction (Oxford, England)
Vol/bind23
Udgave nummer4
Sider (fra-til)775-82
Antal sider8
ISSN0268-1161
DOI
StatusUdgivet - apr. 2008

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