Premorbid teacher-rated social functioning predicts adult schizophrenia-spectrum disorder: a high-risk prospective investigation

Thomas Tsuji, Emily Kline, Holger J Sorensen, Erik L Mortensen, Niels Michelsen, Morten Ekstrom, Sarnoff Mednick, Jason Schiffman

22 Citationer (Scopus)

Abstract

Social functioning deficits are a core component of schizophrenia spectrum disorders, and may emerge years prior to the onset of diagnosable illness. The current study prospectively examines the relation between teacher-rated childhood social dysfunction and later mental illness among participants who were at genetic high-risk for schizophrenia and controls (n=244). The teacher-rated social functioning scale significantly predicted psychiatric outcomes (schizophrenia-spectrum vs. other psychiatric disorder vs. no mental illness). Poor premorbid social functioning appears to constitute a marker of illness vulnerability and may also function as a chronic stressor potentially exacerbating risk for illness.
OriginalsprogEngelsk
TidsskriftSchizophrenia Research
Vol/bind151
Udgave nummer1-3
Sider (fra-til)270-3
Antal sider4
ISSN0920-9964
DOI
StatusUdgivet - dec. 2013

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