Pregnancy outcomes in a cohort of women with a preconception body mass index >50 kg/m²

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Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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@article{7c24dd327fc349fb839a41c22ed5d025,

title = "Pregnancy outcomes in a cohort of women with a preconception body mass index >50 kg/m²",

abstract = "We describe characteristics and risk factors regarding pregnancy outcome in women with a preconception body mass index (BMI) >50 kg/m² compared with women with BMI ≤50 kg/m² in a retrospective population cohort study in singleton pregnancies from the Danish Medical Birth Registry. Results were analyzed as relative risks by a two-proportion z-test. Women with preconception BMI >50 kg/m² smoked, developed gestational diabetes and pre-eclampsia, and needed induction of labor more frequently than mothers with BMI ≤50 kg/m². Examination of the case records showed that many attempted vaginal delivery without epidural analgesia, 21{\%} needed an emergency cesarean section (compared with 12{\%} among women with BMI ≤50 kg/m²), and 25{\%} underwent general anesthesia in this context. Many neonates were macrosomic and 34{\%} needed neonatal intensive care and early feeding compared with 6{\%} of neonates from women with BMI ≤50 kg/m². Women with an extremely high preconception BMI develop more pregnancy complications and their neonates appear affected by this as well.",

keywords = "Adult, Body Mass Index, Cesarean Section, Cohort Studies, Diabetes, Gestational, Female, Humans, Incidence, Obesity, Pre-Eclampsia, Pregnancy, Pregnancy Outcome, Registries, Risk Factors, Smoking",

author = "Barbara Bonnesen and Secher, {Niels J} and M{\o}ller, {Lars K} and Rasmussen, {Bodil Steen} and Andreasen, {Kirsten R} and Kristina Renault",

note = "{\circledC} 2013 Nordic Federation of Societies of Obstetrics and Gynecology.",

year = "2013",

month = "9",

doi = "10.1111/aogs.12174",

language = "English",

volume = "92",

pages = "1111--4",

journal = "Acta Obstetricia et Gynecologica Scandinavica",

issn = "0001-6349",

publisher = "Informa Healthcare",

number = "9",

}

RIS

TY - JOUR

T1 - Pregnancy outcomes in a cohort of women with a preconception body mass index >50 kg/m²

AU - Bonnesen, Barbara

AU - Secher, Niels J

AU - Møller, Lars K

AU - Rasmussen, Bodil Steen

AU - Andreasen, Kirsten R

AU - Renault, Kristina

PY - 2013/9

Y1 - 2013/9

N2 - We describe characteristics and risk factors regarding pregnancy outcome in women with a preconception body mass index (BMI) >50 kg/m² compared with women with BMI ≤50 kg/m² in a retrospective population cohort study in singleton pregnancies from the Danish Medical Birth Registry. Results were analyzed as relative risks by a two-proportion z-test. Women with preconception BMI >50 kg/m² smoked, developed gestational diabetes and pre-eclampsia, and needed induction of labor more frequently than mothers with BMI ≤50 kg/m². Examination of the case records showed that many attempted vaginal delivery without epidural analgesia, 21% needed an emergency cesarean section (compared with 12% among women with BMI ≤50 kg/m²), and 25% underwent general anesthesia in this context. Many neonates were macrosomic and 34% needed neonatal intensive care and early feeding compared with 6% of neonates from women with BMI ≤50 kg/m². Women with an extremely high preconception BMI develop more pregnancy complications and their neonates appear affected by this as well.

AB - We describe characteristics and risk factors regarding pregnancy outcome in women with a preconception body mass index (BMI) >50 kg/m² compared with women with BMI ≤50 kg/m² in a retrospective population cohort study in singleton pregnancies from the Danish Medical Birth Registry. Results were analyzed as relative risks by a two-proportion z-test. Women with preconception BMI >50 kg/m² smoked, developed gestational diabetes and pre-eclampsia, and needed induction of labor more frequently than mothers with BMI ≤50 kg/m². Examination of the case records showed that many attempted vaginal delivery without epidural analgesia, 21% needed an emergency cesarean section (compared with 12% among women with BMI ≤50 kg/m²), and 25% underwent general anesthesia in this context. Many neonates were macrosomic and 34% needed neonatal intensive care and early feeding compared with 6% of neonates from women with BMI ≤50 kg/m². Women with an extremely high preconception BMI develop more pregnancy complications and their neonates appear affected by this as well.

KW - Adult

KW - Body Mass Index

KW - Cesarean Section

KW - Cohort Studies

KW - Diabetes, Gestational

KW - Female

KW - Humans

KW - Incidence

KW - Obesity

KW - Pre-Eclampsia

KW - Pregnancy

KW - Pregnancy Outcome

KW - Registries

KW - Risk Factors

KW - Smoking

U2 - 10.1111/aogs.12174

DO - 10.1111/aogs.12174

M3 - Journal article

VL - 92

SP - 1111

EP - 1114

JO - Acta Obstetricia et Gynecologica Scandinavica

JF - Acta Obstetricia et Gynecologica Scandinavica

SN - 0001-6349

IS - 9

ER -

ID: 42695276

Pregnancy outcomes in a cohort of women with a preconception body mass index >50 kg/m²

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