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Pregnancy outcomes following oocyte donation

Publikation: Bidrag til tidsskriftReviewpeer review

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@article{14082207e4a74815881670440363c106,
title = "Pregnancy outcomes following oocyte donation",
abstract = "The use of oocyte donation (OD) has increased continuously over the last three decades, and it is now an indispensable part of assisted reproductive technology (ART). With OD, it has become possible to overcome the biological barrier of ovarian follicle pool depletion and the general age-related decline in fertility. This review contains a thorough appraisal of the safety of OD with an analysis of short-term pregnancy outcomes. Salient up-to-date evidence was evaluated, which revealed that in comparison with both IVF with autologous oocytes, and naturally conceived pregnancies, there is: (i) an increased risk of hypertensive disorders of pregnancy and preeclampsia; (ii) an increased risk of low birth weight and preterm birth and (iii) an increased risks of obstetric emergencies, following OD treatment. As a precaution, it is therefore highly encouraged to perform only single embryo transfer (SET) and to prescribe prophylactic low-dose aspirin during OD pregnancies.",
keywords = "Aspirin, Assisted reproductive technique, Donor conception, Oocyte donation, Pregnancy complications, Pregnancy-induced hypertension",
author = "Sine Berntsen and Larsen, {Elisabeth Clare} and {la Cour Freiesleben}, Nina and Anja Pinborg",
note = "Copyright {\textcopyright} 2020. Published by Elsevier Ltd.",
year = "2021",
month = jan,
doi = "10.1016/j.bpobgyn.2020.07.008",
language = "English",
volume = "70",
pages = "81--91",
journal = "Best Practice and Research in Clinical Obstetrics and Gynaecology",
issn = "1521-6934",
publisher = "Bailliere Tindall",

}

RIS

TY - JOUR

T1 - Pregnancy outcomes following oocyte donation

AU - Berntsen, Sine

AU - Larsen, Elisabeth Clare

AU - la Cour Freiesleben, Nina

AU - Pinborg, Anja

N1 - Copyright © 2020. Published by Elsevier Ltd.

PY - 2021/1

Y1 - 2021/1

N2 - The use of oocyte donation (OD) has increased continuously over the last three decades, and it is now an indispensable part of assisted reproductive technology (ART). With OD, it has become possible to overcome the biological barrier of ovarian follicle pool depletion and the general age-related decline in fertility. This review contains a thorough appraisal of the safety of OD with an analysis of short-term pregnancy outcomes. Salient up-to-date evidence was evaluated, which revealed that in comparison with both IVF with autologous oocytes, and naturally conceived pregnancies, there is: (i) an increased risk of hypertensive disorders of pregnancy and preeclampsia; (ii) an increased risk of low birth weight and preterm birth and (iii) an increased risks of obstetric emergencies, following OD treatment. As a precaution, it is therefore highly encouraged to perform only single embryo transfer (SET) and to prescribe prophylactic low-dose aspirin during OD pregnancies.

AB - The use of oocyte donation (OD) has increased continuously over the last three decades, and it is now an indispensable part of assisted reproductive technology (ART). With OD, it has become possible to overcome the biological barrier of ovarian follicle pool depletion and the general age-related decline in fertility. This review contains a thorough appraisal of the safety of OD with an analysis of short-term pregnancy outcomes. Salient up-to-date evidence was evaluated, which revealed that in comparison with both IVF with autologous oocytes, and naturally conceived pregnancies, there is: (i) an increased risk of hypertensive disorders of pregnancy and preeclampsia; (ii) an increased risk of low birth weight and preterm birth and (iii) an increased risks of obstetric emergencies, following OD treatment. As a precaution, it is therefore highly encouraged to perform only single embryo transfer (SET) and to prescribe prophylactic low-dose aspirin during OD pregnancies.

KW - Aspirin

KW - Assisted reproductive technique

KW - Donor conception

KW - Oocyte donation

KW - Pregnancy complications

KW - Pregnancy-induced hypertension

U2 - 10.1016/j.bpobgyn.2020.07.008

DO - 10.1016/j.bpobgyn.2020.07.008

M3 - Review

C2 - 32741624

VL - 70

SP - 81

EP - 91

JO - Best Practice and Research in Clinical Obstetrics and Gynaecology

JF - Best Practice and Research in Clinical Obstetrics and Gynaecology

SN - 1521-6934

ER -

ID: 60589056