@article{b4b82967d3914b39ab7494372cd3e2c9,
title = "Predictive impact of RRM1 protein expression on vinorelbine efficacy in NSCLC patients randomly assigned in a chemotherapy phase III trial",
abstract = "Platinum-based doublets (PBDs) remain the cornerstone of treatment in non-small-cell lung cancer (NSCLC) and may include gemcitabine. A biomarker predicting sensitivity to this antimetabolite would represent a major step forward. Accordingly, we explored the predictive role of ribonucleotide reductase subunit M (RRM1) in advanced NSCLC.",
keywords = "Adult, Aged, Antineoplastic Agents, Phytogenic, Antineoplastic Combined Chemotherapy Protocols, Carcinoma, Non-Small-Cell Lung, Cisplatin, Deoxycytidine, Disease-Free Survival, Female, Humans, Lung Neoplasms, Male, Middle Aged, Paclitaxel, Prognosis, Radiation-Sensitizing Agents, Survival Rate, Tumor Markers, Biological, Tumor Suppressor Proteins, Vinblastine, Young Adult",
author = "Vilmar, {A C} and E Santoni-Rugiu and Sorensen, {J B}",
year = "2013",
month = feb,
doi = "10.1093/annonc/mds335",
language = "English",
volume = "24",
pages = "309--14",
journal = "Annals of oncology : official journal of the European Society for Medical Oncology / ESMO",
issn = "0923-7534",
publisher = "Oxford University Press",
number = "2",
}