Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Prediction of mortality at age 40 in Danish males at high and low risk for alcoholism

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Trajectory of cognitive functions in bipolar disorder: for better or worse?

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Incidence of suicidal behaviour and violent crime following antidepressant medication: a Danish cohort study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Response to comment on Osler et al: misinterpretation of pre- and post differences invalidate the authors' conclusion

    Publikation: Bidrag til tidsskriftKommentar/debatForskningpeer review

  4. Societal costs of Borderline Personality Disorders: a matched-controlled nationwide study of patients and spouses

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Meta-analysis of antidepressant effects of anti-inflammatory drugs-reply

    Publikation: Bidrag til tidsskriftKommentar/debatForskningpeer review

  1. Maintenance of muscle strength following a one-year resistance training program in older adults

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Using the Cultural Formulation Interview in Denmark: Acceptability and clinical utility for medical doctors and migrant patients

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. The influence of prolonged strength training upon muscle and fat in healthy and chronically diseased older adults

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

OBJECTIVE: This prospective high-risk study examined the influence of father's alcoholism and other archival-generated measures on premature death.

METHOD: Sons of alcoholic fathers (n = 223) and sons of non-alcoholic fathers (n = 106) have been studied from birth to age 40. Archival predictors of premature death included father's alcoholism, childhood developmental data, and diagnostic information obtained from the Psychiatric Register and alcoholism clinics.

RESULTS: By age 40, 21 of the 329 subjects had died (6.4%), a rate that is more than two times greater than expected. Sons of alcoholic fathers were not more likely to die by age 40. Premature death was associated with physical immaturity at 1-year of age and psychiatric/alcoholism treatment. No significant interactions were found between risk and archival measures.

CONCLUSION: Genetic vulnerability did not independently predict death at age 40. Death was associated with developmental immaturities and treatment for a psychiatric and/or substance abuse problem.

OriginalsprogEngelsk
TidsskriftActa Psychiatrica Scandinavica
Vol/bind110
Udgave nummer6
Sider (fra-til)476-82
Antal sider7
ISSN0001-690X
DOI
StatusUdgivet - dec. 2004

ID: 46035140